Browsing by Author "Hatemi, Hüsrev"
Now showing items 1-5 of 5
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Apolipoprotein B gene variants are involved in the determination of blood glucose and lipid levels in patients with non-insulin dependent diabetes mellitus
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Publisher and Date:(Wiley, 2006)We have examined the frequency of the EcoRI XbaI and MspI RFLPs of the apolipoprotein B (apo 13) gene in I 10 type 2 diabetic patients and 9 1 healthy control subjects in order to ascertain whether variation in this gene may influence the development of non-insulin dependent diabetes mellitus (type 2 diabetes). Serum lipids including total-cholesterol (T-Chol) triacylglycerol (TAG) apolipoprotein E (apo E) apolipoprotein Al (apo Al) apolipoprotein B and lipoprotein (a) (Lp(a)) were analysed. Genomic ...
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Apolipoprotein E polymorphism in Turkish subjects with Type 2 diabetes mellitus: Allele frequency and relation to serum lipid concentrations
Authors:
Publisher and Date:(EDITRICE KURTIS S R L, 2004)The role of apolipoprotein E (apoE) genotypes in modulating plasma lipid and apolipoprotein levels was studied in 112 patients with Type 2 diabetes mellitus (T2DM) and 94 healthy individuals. ApoE genotypes were identified by PCR amplification and subsequent restriction endonuclease digestion. The apoE allele and genotype frequencies were similar in both the diabetic and control subjects. The apoE allele frequencies were found to be 74.3 for e3 10.1 for e2 15.6 for e4 in the diabetic group and ...
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DNA polymorphism of Pvu II site in the lipoprotein lipase gene in patients with non-insulin dependent diabetes mellitus
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Publisher and Date:(Wiley, 2005)We studied the effect of variation at the lipoprotein lipase (LPL) gene locus on the susceptibility of individuals with non-insulin dependent diabetes mellitus (NIDDM) in a population of 110 NIDDM patients and 91 controls. Our objective was to study the relationship between the LPL-Pvu II polymorphism and NIDDM and lipid metabolism. PCR-RFLP was used to determine the DNA polymorphism of the sixth intron of the LPL gene. The frequencies of the genotypes in case and control groups were 29.1 and 30.8% ...
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Hyperuricemia in hypothyroidism: Is it associated with post-insulin infusion glycemic response?
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Publisher and Date:(Tohoku Univ Medical Press, 2003)This experimental study was designed to examine whether hyperuricemia in hypothyroidism is associated with insulin resistance. For induction of hypothyroidism rabbits (n = 12) were administered methimazole orally (75 mg/100 g food) for 30 days. T-3 T-4 and TSH values measured in plasma prior to and at the end of the experimentation period revealed the establishment of hypothyroidism. In the euthyroid and hypothyroid states of rabbits crystalline porcine insulin was administered (0.1 unit/kg body ...
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Thiols malonaldehyde status in the Turkish and total antioxidant patients with type 2 diabetes mellitus
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Publisher and Date:(Tohoku Univ Medical Press, 2003)Non-insulin-dependent (Type 2) diabetes mellitus (NIDDM) is a risk factor for cardiovascular diseases (CVD). Oxidative stress mechanisms are often reported to be implied in type 2 diabetes mellitus. In order to determine their clinical relevance we investigated several plasma indicators in the Turkish patients with NIDDM: (1) homocysteine (Hey) and cysteine (Cys) which contribute to increase the risk of atherosclerosis during NIDDM (ii) glutathione (GSH) and cysteinylglycine (CysGly) resulting ...
