Browsing by Author "Tanakol, Refik"
Now showing items 1-2 of 2
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Polymorphisms at the ligand binding site of the vitamin D receptor gene and osteomalacia
Authors:
Publisher and Date:(Hindawi Ltd, 2005)Vitamin D receptor (VDR) gene polymorphisms have been suggested as possible determinants of bone mineral density (BMD) and calcium metabolism. In this study our aim was to determine whether there is an association between VDR gene polymorphism and osteomalacia or not. We determined ApaI and TaqI polymorphisms in the vitamin D receptor gene in 24 patients with osteomalacia and 25 age-matched healthy controls. Serum calcium phosphorus ALP PTH 25OHD levels were also examined. We used PCR and RFLP ...
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Vitamin D receptor alleles bone mineral density and turnover in postmenopausal osteoporotic and healthy women
Authors:
Publisher and Date:(Karger, 2004)Objective: Vitamin D receptor (VDR) gene polymorphisms and bone metabolic markers were investigated as potential genetic markers for osteoporosis in postmenopausal Turkish women. The relationship between their VDR gene polymorphisms and bone states was determined. Materials and Methods: Restriction fragment length polymorphisms at the VDR gene locus (i.e. for BsmI ApaI and TaqI) was investigated in 75 postmenopausal osteoporotic (53.16+/-1.31 years) and 66 healthy (52.62+/-1.69 years) Turkish women ...
