Browsing by Author "Vertii, Alexey"
Authors:Duman, Belgin Süsleyici; Türkoğlu, Caner; Akpinar, Belhhan; Güden, Mustafa; Vertii, Alexey; Dak, Esranur; Çağatay, Tülin; Günay, Demet; Buyukdevrim, Ahmet Sevim
Publisher and Date:(COLL AMER PATHOLOGISTS, 2004)Context.-Lipoprotein lipase (LPL) plays a central role in lipid metabolism hydrolyzing triglyceride in chylomicrons and very-low-density lipoproteins. The PvuII polymorphic variant of LPL gene is common and might affect risk of coronary artery disease (CAD). Objective.-Our aim was to determine whether LPL-PvuII polymorphism can be considered to be an independent risk factor or a predictor for CAD in Turkish subjects. Design.-We used polymerase chain reaction and restriction enzyme digestion to ...