Browsing by Publisher "Oxford University Press"
Now showing items 1-13 of 13
-
BEAMS: backbone extraction and merge strategy for the global many-to-many alignment of multiple PPI networks
Authors:
Publisher and Date:(Oxford University Press, 2014)Motivation: Global many-to-many alignment of biological networks has been a central problem in comparative biological network studies. Given a set of biological interaction networks the informal goal is to group together related nodes. For the case of protein-protein interaction networks such groups are expected to form clusters of functionally orthologous proteins. Construction of such clusters for networks from different species may prove useful in determining evolutionary relationships in ...
-
Biomarkers of Secondhand Smoke Exposure in Waterpipe Tobacco Venue Employees in Istanbul Moscow and Cairo
Authors:
Publisher and Date:(Oxford University Press, 2018)Background: Most smoke-free legislation to reduce secondhand smoke (SHS) exposure exempts waterpipe (hookah) smoking venues. Few studies have examined SHS exposure in waterpipe venues and their employees. Methods: We surveyed 276 employees of 46 waterpipe tobacco venues in Istanbul Moscow and Cairo. We interviewed venue managers and employees and collected biological samples from employees to measure exhaled carbon monoxide (CO) hair nicotine saliva cotinine urine cotinine urine 4-(methylnitrosa ...
-
CAMPways: constrained alignment framework for the comparative analysis of a pair of metabolic pathways
Authors:
Publisher and Date:(Oxford University Press, 2013)Motivation: Given a pair of metabolic pathways an alignment of the pathways corresponds to a mapping between similar substructures of the pair. Successful alignments may provide useful applications in phylogenetic tree reconstruction drug design and overall may enhance our understanding of cellular metabolism. Results: We consider the problem of providing one-to-many alignments of reactions in a pair of metabolic pathways. We first provide a constrained alignment framework applicable to the problem. ...
-
Combined radiofrequency modified maze and mitral valve procedure through a port access approach: early and mid-term results
Authors:
Publisher and Date:(Oxford University Press, 2003)Objective: The aim of this study was to assess the feasibility and effectiveness of irrigated radiofrequency (RF) modified Maze procedure through a port access approach during mitral valve surgery and evaluate early and mid-term results. Material and method: During a 16 months time period 67 patients with chronic atrial fibrillation (AF) eligible for port access mitral valve surgery were randomly assigned to either Group A in which they underwent a combined procedure (N = 33) or Group B in which ...
-
Factors That Influence Support and Enforcement of the Smoke-Free Law in Turkey
Authors:
Publisher and Date:(Oxford University Press, 2016)
-
Improving performances of suboptimal greedy iterative biclustering heuristics via localization
Authors:
Publisher and Date:(Oxford University Press, 2010)Motivation: Biclustering gene expression data is the problem of extracting submatrices of genes and conditions exhibiting significant correlation across both the rows and the columns of a data matrix of expression values. Even the simplest versions of the problem are computationally hard. Most of the proposed solutions therefore employ greedy iterative heuristics that locally optimize a suitably assigned scoring function. Methods: We provide a fast and simple pre-processing algorithm called ...
-
Introducing a Fairness-Based Theory of Prosecutorial Legitimacy Before The International Criminal Court
Authors:
Publisher and Date:(Oxford University Press, 2016)The International Criminal Court became operative in 2002. The first prosecutor of the Court faced the enormous challenge of setting up a series of policies addressing at the same time the backlog of overriding expectations. His task was daunting and his prosecutorial choices triggered a series of controversies among a variety of relevant audiences while the concept of legitimacy appeared to become the panacea to the debate. The current contribution purports to achieve a twofold goal using a ...
-
Macroeconomic and institutional determinants of financialisation of non-financial firms: Case study of Turkey
Authors:
Publisher and Date:(Oxford University Press, 2014)We observe that industrial firms in Turkey have shifted substantial amounts of working capital from production activities to the purchase of high-yield interest-bearing assets most notably public bonds to ensure immediate short-term interest revenues. Introducing the new and historical institutional literatures to the financialisation research this article empirically examines the influences of macroeconomic and institutional factors on non-financial firms' financialisation behaviour for the period ...
-
Nearly a decade on - The perception of international arbitration law by Turkish Courts
Authors:
Publisher and Date:(Oxford University Press, 2010)
-
RedNemo: topology-based PPI network reconstruction via repeated diffusion with neighborhood modifications
Authors:
Publisher and Date:(Oxford University Press, 2017)Motivation: Analysis of protein-protein interaction (PPI) networks provides invaluable insight into several systems biology problems. High-throughput experimental techniques together with computational methods provide large-scale PPI networks. However a major issue with these networks is their erroneous nature
-
Reliability-Oriented bioinformatic networks visualization
Authors:
Publisher and Date:(Oxford University Press, 2011)We present our protein-protein interaction (PPI) network visualization system RobinViz (reliability-oriented bioinformatic networks visualization). Clustering the PPI network based on gene ontology (GO) annotations or biclustered gene expression data providing a clustered visualization model based on a central/peripheral duality computing layouts with algorithms specialized for interaction reliabilities represented as weights completely automated data acquisition processing are notable features ...
-
SiPAN: simultaneous prediction and alignment of protein-protein interaction networks
Authors:
Publisher and Date:(Oxford University Press, 2015)Motivation: Network prediction as applied to protein-protein interaction (PPI) networks has received considerable attention within the last decade. Because of the limitations of experimental techniques for interaction detection and network construction several computational methods for PPI network reconstruction and growth have been suggested. Such methods usually limit the scope of study to a single network employing data based on genomic context structure domain sequence information or existing ...
-
SPINAL: scalable protein interaction network alignment
Authors:
Publisher and Date:(Oxford University Press, 2013)Motivation: Given protein-protein interaction (PPI) networks of a pair of species a pairwise global alignment corresponds to a one-to-one mapping between their proteins. Based on the presupposition that such a mapping provides pairs of functionally orthologous proteins accurately the results of the alignment may then be used in comparative systems biology problems such as function prediction/verification or construction of evolutionary relationships. Results: We show that the problem is NP-hard ...
