Browsing by Publisher "Scientific Technical Research Council Turkey-Tubitak"
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Aryl butenoic acid derivatives as a new class of histone deacetylase inhibitors: synthesis in vitro evaluation and molecular docking studies Authors :
Publisher and Date : (Scientific Technical Research Council Turkey-Tubitak, 2014)New aryl butenoic acid derivatives have been synthesized by combining hydroxy- or methoxy-substituted phenyl rings as the capping group with a double bond in the short linker as well as metal binding groups enoic ester and ...
Publisher and Date : (Scientific Technical Research Council Turkey-Tubitak, 2011)Histone lysine-specific demethylase (LSD1) is involved in a wide range of epigenetic processes and plays important roles in gene silencing DNA transcription DNA replication DNA repair and heterochromatin formation. Its ...
Power of inhibition activity screening and 3D molecular modeling approaches in HDAC 8 inhibitor design Authors :
Publisher and Date : (Scientific Technical Research Council Turkey-Tubitak, 2011)In-vitro inhibition activity screening and in-silico 3D molecular modeling approaches are important tools for design and development of specific histone deacetylase (HDAC) inhibitors. The objective of this study was to ...
The Dikili-Candarli volcanics Western Turkey: Magmatic interactions as recorded by petrographic and geochemical features Authors :
Publisher and Date : (Scientific Technical Research Council Turkey-Tubitak, 2007)Located in the northwestern part of the Aegean region Dikili- Candarli volcanic suite contains products representative for the western Anatolian Miocene volcanism. They can be divided into two main groups: the Dikili and ...