Browsing by Subject "Aging"
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Publisher and Date:(Institute of Electrical and Electronics Engineers Inc., 2021)Various studies have shown that immune system inspired hypermutation operators can allow artificial immune systems (AIS) to be very efficient at escaping local optima of multimodal optimisation problems. However, this efficiency comes at the expense of considerably slower runtimes during the exploitation phase compared to standard evolutionary algorithms. We propose modifications to the traditional ‘hypermutations with mutation potential’ (HMP) that allow them to be efficient at exploitation as ...
Publisher and Date:(Association for Computing Machinery, 2018)Down syndrome (DS) which affects approximately one in 700 live births is caused by an extra copy of the long arm of human chromosome 21 (HSA21). Statistical analysis has been done for understanding the protein expression profiles based on age and sex differences in DS. In addition there are ongoing research efforts for comprehending expression patterns based on different brain regions. However little is known about the mechanisms of expression differences in brain regions throughout aging. Insights ...