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  • Importance of Regional Differences in Brain Throughout Aging for Down Syndrome 

    Down syndrome (DS) which affects approximately one in 700 live births is caused by an extra copy of the long arm of human chromosome 21 (HSA21). Statistical analysis has been done for understanding the protein expression profiles based on age and sex differences in DS. In addition there are ongoing research efforts for comprehending expression patterns based on different brain regions. However little is known about the mechanisms of expression differences in brain regions throughout aging. Insights ...