Browsing Araştırma Çıktıları / WOS by Author "Yanardağ, Refiye"
Authors:Koyutürk, Meral; Tunali, Sevim; Bolkent, Şehnaz; Yanardağ, Refiye
Publisher and Date:(Humana Press Inc., 2005)The aim of this study was to investigate the microscopic and biochemical effects of vanadyl sulfate on liver tissue of normal and streptozotocin (65 mg/kg) diabetic rats. Vanadyl sulfate was administered by gavage at a dose of 100 mg/kg. Degenerative changes were observed in diabetic animals by light and transmission electron microscopes. Although there were individual differences in diabetic animals to which vanadium was given some reduction of degenerative changes were detected. After 60 d of ...
Authors:Koyutürk, Meral; Yanardağ, Refiye; Bolkent, Şehnaz; Tunali, Sevim
Publisher and Date:(Elsevier Science Bv, 2006)Acute effects ofcadmium (Cd) and combined antioxidants were evaluated in Sprague-Dawley rat testes. The rats were subdivided into four groups. Cadmium chloride (2 mg/kg day) injected intraperitoneally during 8 days. Vitamin C (250 mg/kg day) vitamin E (250 rng/kgday) and sodium selenate (0.25 mg/kg day) were pretreated by gavage in both ofcontrol and cadmium injected rats. Testis lipid peroxidation and glutathione levels were determined by spectrophotometrically. In Cd treated rats lipid peroxidation ...
The protective effect of vitamin C vitamin E and selenium combination therapy on ethanol-induced duodenal mucosal injury Authors:Koyutürk, Meral; Bolkent, Şehnaz; Özdil, S; Arbak, Serap; Yanardağ, Refiye
Publisher and Date:(Arnold Hodder Headline Plc., 2004)In this study the effect of a combination of vitamin C vitamin E and selenium on ethanol-induced duodenal mucosal damage in rats was investigated morphologically and biochemically. The duodenal mucosal injury was produced by oral administration of 1 mL of absolute ethanol to each rat. Animals received vitamin C ( 250 mg/ kg) vitamin E ( 250 mg/kg) and selenium (0.5 mg/kg) for 3 days and absolute ethanol 1 hour after last antioxidant administration and were sacrificed 1 hour after absolute ethanol. ...