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Pharmacophore-based virtual screening for identification of potential selective inhibitors of human histone deacetylase 6 

Uba, Abdullahi Ibrahim; Yelekçi, Kemal (Elsevier Sci Ltd, 2018)
Histone deacetylase (HDAC) 6 plays a role in oncogenic transformation and cancer metastasis via tubulin deacetylation, making it a critical target for anticancer drug design. However, lack of selectivity shown by many of ...

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Author
Uba, Abdullahi Ibrahim (1)
Yelekçi, Kemal (1)
Subject
3D-common feature hypotheses (1)
HDAC6 catalytic domain 2 (1)HDAC6-selective inhibitors (1)Molecular docking (1)
Molecular dynamics simulation (1)
... View MoreDate Issued2018 (1)Has File(s)
false (1)

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