Browsing Araştırma Çıktıları / WOS by Author "Akalın, Halis"
Effect of low-dose methyl prednisolone on serum cytokine levels following extracorporeal circulation Authors:Yılmaz, Mert; Ener, Serdar; Akalın, Halis; Sağdıç, Kadir; Serdar, O. Akin; Cengiz, Mete
Publisher and Date:(Arnold Hodder Headline Plc., 1999)The systemic inflammatory response to cardiopulmonary bypass (CPB) is associated with increased production of cytokines. This systemic inflammatory response characterized by the activation of interleukin-6 (IL-6) and interleukin-8 (IL-8) during and after CPB is well documented. A prospective randomized double-blind study was performed so as to understand the effects of low-dose methyl prednisolone sodium succinate (MPSS) on the circulating levels of serum cytokines and clinical outcome. Twenty ...