Browsing Tez Koleksiyonu by Author "Gökhan Eşsiz, Şebnem"
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Homology modeling and normal mode analysis of human NR1-NR2A NMDA type receptors
Demir, Ayhan S. (Kadir Has Üniversitesi, 2017)N-Methyl-D-Aspartate (NMDA) receptors are ionotropic glutamate receptors located in the membrane of the nerve cells. The normal receptor activity has a vital importance in consciousness and normal brain functions. Neuronal ... -
Structural studies of nmda receptor and xanthine oxidase enzyme
Gencel, Melis (Kadir Has Üniversitesi, 2019)The first part of the thesis deals with the structural studies of N-Methyl-D-Aspartate receptors (NMDARs). NMDARs are ionotropic ligand-gated receptors that have pivotal roles at the central neuronal system but, hyperactivity ... -
Structural study of gaba type a receptor : the effect of intrasubunit disulphide bridges on dynamics
Ayan, Meral (Kadir Has Üniversitesi, 2014)In the mammalian brain the gamma-aminobutyric acid type A receptor is the most commonly expressed subtype of receptor family. Although there is a rich pharmacological activity of R, specific molecular features are still ...