Browsing PubMed İndeksli Yayınlar Koleksiyonu by Title
Now showing items 245-264 of 378
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New azole derivatives showing antimicrobial effects and their mechanism of antifungal activity by molecular modeling studies
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)Azole antifungals are potent inhibitors of fungal lanosterol 14 alpha demethylase (CYP51) and have been used for eradication of systemic candidiasis clinically. Herein we report the design synthesis and biological evaluation ... -
New Biological and Chemical Evidences of Two Lamiaceae Species (Thymbra capitata and Thymus sipyleus subsp. rosulans): In Vitro, In Silico and Ex Vivo Approaches
(Mdpi, 2022)In this study, the methanolic and infusion extracts of two species, Thymbra capitata and Thymus sipyleus subsp. rosulans, were tested for their chemical composition and biological abilities (antioxidant, enzyme inhibitory ... -
New Human Monoamine Oxidase A Inhibitors with Potential Anti- Depressant Activity: Design, Synthesis, Biological Screening and Evaluation of Pharmacological Activity
(Bentham Science, 2017)Aim and objective: Depression is a momentous disease that can greatly reduce the quality of life and cause death. In depression, neurotransmitter levels such as serotonine, dopamine and noradrenaline are impaired. Monoamine ... -
New insights from children with early focal brain injury: Lessons to be learned from examining STEM-related skills
(Wiley, 2019)The study of cognitive development in children with early brain injury reveals crucial information about the developing brain and its plasticity. However information on long-term outcomes of these children especially in ... -
New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes
(Company of Biologists Ltd, 2017)Cytoplasmic FMRP interacting protein 1 (CYFIP1) is a candidate gene for intellectual disability (ID) autism schizophrenia and epilepsy. It is a member of a family of proteins that is highly conserved during evolution sharing ... -
A new lung cancer detection method based on the chest CT images using Federated Learning and blockchain systems
(Elsevier, 2023)With an estimated five million fatal cases each year, lung cancer is one of the significant causes of death worldwide. Lung diseases can be diagnosed with a Computed Tomography (CT) scan. The scarcity and trustworthiness ... -
New modification in otoplasty: Anterior approach
(Lippincott Williams & Wilkins, 2001)After harvesting the conchal cartilage in a large series of secondary rhinoplasties using the anterior approach there was a marked improvement in the shape of the auricle with unnoticeable scarring hidden under the convolution ... -
New pyrazoline bearing 4(3H)-quinazolinone inhibitors of monoamine oxidase: Synthesis biological evaluation and structural determinants of MAO-A and MAO-B selectivity
(Pergamon-Elsevier Science Ltd, 2009)A new series of pyrazoline derivatives were prepared starting from a quinazolinone ring and evaluated for antidepressant anxiogenic and MAO-A and -B inhibitory activities by in vivo and in vitro tests respectively. Most ... -
A new technique for abdominal heart transplantation in rats
(Edizioni Minerva Medica, 2003)Experimental studies in animals play a major role in the progress of medicine. Different surgical techniques have been described for heterotopic heart transplantation in rats. in this study we introduce a new technique for ... -
A new triazolothiadiazine derivative inhibits stemness and induces cell death in HCC by oxidative stress dependent JNK pathway activation
(Nature Portfolio, 2022)Hepatocellular carcinoma (HCC) is a highly heterogeneous cancer, and resistant to both conventional and targeted chemotherapy. Recently, nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to decrease the incidence ... -
Novel 1,2,4-triazoles derived from Ibuprofen: synthesis and in vitro evaluation of their mPGES-1 inhibitory and antiproliferative activity
(Springer, 2022)Some novel triazole-bearing ketone and oxime derivatives were synthesized from Ibuprofen. In vitro cytotoxic activities of all synthesized molecules against five cancer lines (human breast cancer MCF-7, human lung cancer ... -
Novel Application Software for the Semi-Automated Analysis of Infrared Meibography Images
(2019)Purpose: To develop semi-automated application software that quickly analyzes infrared meibography images taken with the CSO Sirius Topographer (CSO, Italy) and to compare them to the manual analysis system on the device ... -
Novel Mutants of the Aubergine Gene
(Taylor & Francis Inc, 2016)Aubergine is an RNA-binding protein of the Piwi clade functioning in germline in the piRNA pathway that silences transposons and repetitive sequences. Several mutations of this gene exist but they mostly result in truncated ... -
Off-pump coronary artery bypass grafting with use of the octopus 2 stabilization system
(2000)Background: The treatment of coronary artery disease has evolved rapidly over the last two decades. The gold standard of surgical revascularization, the on-pump coronary artery bypass graft, has been challenged by the ... -
On the uniqueness of epidemic models fitting a normalized curve of removed individuals
(Springer Heidelberg, 2015)The susceptible-infected-removed (SIR) and the susceptible-exposed-infected-removed (SEIR) epidemic models with constant parameters are adequate for describing the time evolution of seasonal diseases for which available ... -
Ondansetron hydrochloride for the treatment of delirium after coronary artery surgery
(Mosby Inc, 2001)[Abstract Not Available] -
One-stage surgical correction of congenital thoracic lordosis - report of 2 cases
(Taylor & Francis, 2001)[Abstract Not Available] -
An online diary study testing the role of functional and dysfunctional self-licensing in unhealthy snacking
(Academic Press, 2023)In the present study, we aimed to investigate how two types of self-licensing (functional and dysfunctional self-licensing) are related to unhealthy snack consumption. Self-licensing refers to the act of using justifications ... -
Optical spatial modulation design
(Royal Soc, 2020)Visible light communication (VLC) systems are inherently signal-to-noise ratio (SNR) limited due to link budget constraints. One favourable method to overcome this limitation is to focus on the pre-log factors of the channel ...