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Synthesis and molecular modeling of some novel hexahydroindazole derivatives as potent monoamine oxidase inhibitors
(Pergamon-Elsevier Science Ltd, 2009)
A novel series of 2-thiocarbamoyl-234567-hexahydro-1H-indazole and 2-substituted thiocarbamoyl-33a 4567-hexahydro-2H-indazoles derivatives were synthesized and investigated for the ability to inhibit the activity of the A ...
A Docking Study Using Atomistic Conformers Generated via Elastic Network Model for Cyclosporin A/Cyclophilin A Complex
(Taylor & Francis Inc, 2009)
Anisotropic network model is used to generate a set of distinct conformations for cylophilin A (CypA). The native structure is deformed to different extents along each of the lowest-frequency modes (first 7 modes) both in ...
Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies
(Pergamon-Elsevier Science Ltd, 2009)
In the light of known HDAC inhibitors 33 carboxylic acid derivatives were tested to understand the structural requirements for HDAC inhibition activity. Several modifications were applied to develop the structure-activity ...
Combined radiofrequency modified maze and mitral valve procedure through a port access approach: early and mid-term results
(Oxford University Press, 2003)
Objective: The aim of this study was to assess the feasibility and effectiveness of irrigated radiofrequency (RF) modified Maze procedure through a port access approach during mitral valve surgery and evaluate early and ...
Comparison of intraoperative transit-time flow measurement with early postoperative magnetic resonance flow mapping - in off-pump coronary artery surgery
(Texas Heart Inst., 2003)
The purpose of this prospective study was to evaluate graft patency of off-pump coronary artery surgery intraoperatively by transit-time flow measurement and to compare this technique with postoperative magnetic resonance ...
Influence of cardiovascular risk factors on the outcome of coronary artery bypass surgery
(Springer Verlag, 2003)
Purpose. To assess the impact of gender age and other cardiovascular risk factors on the outcomes of patients undergoing coronary artery bypass grafting (CABG). Methods. A total of 5 067 consecutive patients undergoing ...
Antihepatitis B response to hepatitis B vaccine administered simultaneously with tetanus toxoid in nonresponder individuals
(Elsevier Science, 2002)
In this prospective study our aim was to test the effect of simultaneous administration of preS2 and S containing recombinant hepatitis B vaccine (S2SRHB) with tetanus toxoid (TT) to the individuals who did not respond ...
Clinical experience with coronary sinus catheterization in minimally invasive aortic valve surgery under transesophageal echocardiography guidance
(Kluwer Academic Publishers, 2002)
We aimed to show conventional coronary sinus (CS) catheter could be used with transesophageal echocardiography (TEE) guidance through the limited surgical field in aortic valve surgery with 'J' sternotomy. This method was ...
Anterior instrumentation for adolescent idiopathic scoliosis
(Springer Verlag, 2001)
Thirty-two patients with adolescent idiopathic scoliosis underwent anterior fusion with rigid single rod (third generation instrumentation) and titanium mesh cages. The mean follow-up was 31 (24-45) months and the mean age ...
One-stage surgical correction of congenital thoracic lordosis - report of 2 cases
(Taylor & Francis, 2001)
[Abstract Not Available]