Search
Now showing items 21-30 of 378
Drug repurposing for coronavirus (COVID-19): in silico screening of known drugs against coronavirus 3CL hydrolase and protease enzymes
(TAYLOR & FRANCIS LTD, 2020)
In December 2019, COVID-19 epidemic was described in Wuhan, China, and the infection has spread widely affecting hundreds of thousands. Herein, an effort was made to identify commercially available drugs in order to repurpose ...
Metastable reverse-phase droplets within ordered phases: Renormalization-group calculation of field and temperature dependence of limiting size
(AMER PHYSICAL SOC, 2020)
Metastable reverse-phase droplets are calculated by renormalization-group theory by evaluating the magnetization of a droplet under magnetic field, matching the boundary condition with the reverse phase and noting whether ...
Design, Synthesis and In Vitro Cytotoxic Activity of New 6,9-Disubstituted Purine Analogues
(Slovensko Kemijsko Drustvo, 2020)
A series of new 6,9-disubstituted purine analogs with 4-substituted piperazine at C-6 and 4-substituted benzyl at N-9 were designed and synthesized in four steps. All synthesized compounds (7-26) were screened initially ...
The design of potent HIV-1 integrase inhibitors by a combined approach of structure-based virtual screening and molecular dynamics simulation
(Taylor & Francis Ltd, 2018)
Bu araştırmanın amacı, AIDS olarak bilinen insan bağışıklık sistemine etki eden, duraksamayan ve depresif bir hastalığa neden olan HIV-1'in tedavisi için potansiyel inhibitörleri elde etmektir. HIV-1 integraz inhibitörleri, ...
Lipoprotein lipase gene polymorphism and lipid profile in coronary artery disease
(COLL AMER PATHOLOGISTS, 2004)
Context.-Lipoprotein lipase (LPL) plays a central role in lipid metabolism hydrolyzing triglyceride in chylomicrons and very-low-density lipoproteins. The PvuII polymorphic variant of LPL gene is common and might affect ...
The protective effect of vitamin C vitamin E and selenium combination therapy on ethanol-induced duodenal mucosal injury
(Arnold Hodder Headline Plc., 2004)
In this study the effect of a combination of vitamin C vitamin E and selenium on ethanol-induced duodenal mucosal damage in rats was investigated morphologically and biochemically. The duodenal mucosal injury was produced ...
Pyoderma gangrenosum at the incision site following gynecologic surgery
(ELSEVIER SCI IRELAND LTD, 2004)
[Abstract Not Available]
Myositis ossificans of psoas muscle: Magnetic resonance imaging findings
(Blackwell Munksgaard, 2004)
Myositis ossificans is a benign localized self-limiting ossifying soft tissue mass with unknown pathogenesis. It may be confused with a malignant tumor of bone or soft tissues especially in the early stages of the disease. ...
Apolipoprotein E polymorphism in Turkish subjects with Type 2 diabetes mellitus: Allele frequency and relation to serum lipid concentrations
(EDITRICE KURTIS S R L, 2004)
The role of apolipoprotein E (apoE) genotypes in modulating plasma lipid and apolipoprotein levels was studied in 112 patients with Type 2 diabetes mellitus (T2DM) and 94 healthy individuals. ApoE genotypes were identified ...
Effects of vanadyl sulfate on liver of streptozotocin-induced diabetic rats
(Humana Press Inc., 2005)
The aim of this study was to investigate the microscopic and biochemical effects of vanadyl sulfate on liver tissue of normal and streptozotocin (65 mg/kg) diabetic rats. Vanadyl sulfate was administered by gavage at a ...