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Synthesis, Anticancer Activity on Prostate Cancer Cell Lines and Molecular Modeling Studies of Flurbiprofen-Thioether Derivatives as Potential Target of MetAP (Type II)
(Bentham Science PUBL LTD, 2020)
Background: Prostate cancer is still one of the serious causes of mortality and morbidity in men. Despite recent advances in anticancer therapy, there is a still need of novel agents with more efficacy and specificity in ...
New 2-Pyrazoline and Hydrazone Derivatives as Potent and Selective Monoamine Oxidase A Inhibitors
(AMER CHEMICAL SOC, 2021-02)
Thirty compounds having 1-[2-(5-substituted-2-benzoxazolinone-3-yl) acetyl]-3,5-disubstitutedphenyl-2-pyrazoline structure and nine compounds having N'-(1,3-disubstitutedphenylallylidene)-2-(5-substituted- 2-benzoxazolin ...
The role of co-regulation of stress in the relationship between perceived partner responsiveness and binge eating: A dyadic analysis
(International Union of Psychological Science, 2020)
The main aim of this study is to investigate whether there are relationships between perceived partner responsiveness (PPR), co-regulation of negative affect between romantic partners and binge eating. Data were collected ...
Photolithography-Based Microfabrication of Biodegradable Flexible and Stretchable Sensors
(Wiley-V C H Verlag Gmbh, 2023)
Biodegradable sensors based on integrating conductive layers with polymeric materials in flexible and stretchable forms have been established. However, the lack of a generalized microfabrication method results in large-sized, ...
Novel 1,2,4-triazoles derived from Ibuprofen: synthesis and in vitro evaluation of their mPGES-1 inhibitory and antiproliferative activity
(Springer, 2022)
Some novel triazole-bearing ketone and oxime derivatives were synthesized from Ibuprofen. In vitro cytotoxic activities of all synthesized molecules against five cancer lines (human breast cancer MCF-7, human lung cancer ...
Gestures Cued by Demonstratives in Speech Guide Listeners' Visual Attention During Spatial Language Comprehension
(Amer Psychological Assoc, 2023)
Gestures help speakers and listeners during communication and thinking, particularly for visual-spatial information. Speakers tend to use gestures to complement the accompanying spoken deictic constructions, such as ...
The effects of prolactin on the immune system, its relationship with the severity of COVID-19, and its potential immunomodulatory therapeutic effect
(Academic Press Ltd- Elsevier Science Ltd, 2023)
Prolactin (PRL) is an endocrine hormone secreted by the anterior pituitary gland that has a variety of physiological effects, including milk production, immune system regulation, and anti-inflammatory effects. Elevated ...
The availability of emergency contraception from family health centers in Turkey
(Elsevier Ireland Ltd, 2022)
Reproductive health care, including contraception, is a fundamental aspect of any public health care system and it is important to reduce barriers to access to all forms of contraception, including emergency contraception. ...
A it-Electron Rich Cage via the Friedel-Crafts Reaction
(Amer Chemical Soc, 2022)
A prism-shaped cage was obtained via the Friedel-Crafts reaction in a 2:3 mixture of trisfuryl and bis-isopropenyl precursors, in a remarkable yield of 40% considering six C-C bonds formed in a one-pot manner. The cage ...
Air quality prediction using CNN plus LSTM-based hybrid deep learning architecture
(Springer Heidelberg, 2022)
Air pollution prediction based on variables in environmental monitoring data gains further importance with increasing concerns about climate change and the sustainability of cities. Modeling of the complex relationships ...