dc.contributor.author | Uba, Abdullahi Ibrahim | |
dc.contributor.author | Zengin, Gokhan | |
dc.contributor.author | Montesano, Domenico | |
dc.contributor.author | Cakilcioglu, Ugur | |
dc.contributor.author | Selvi, Selami | |
dc.contributor.author | Ulusan, Musa Denizhan | |
dc.contributor.author | Caprioli, Giovanni | |
dc.date.accessioned | 2023-10-19T15:12:02Z | |
dc.date.available | 2023-10-19T15:12:02Z | |
dc.date.issued | 2022 | |
dc.identifier.issn | 2076-3417 | |
dc.identifier.uri | https://doi.org/10.3390/app12136561 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12469/5322 | |
dc.description.abstract | In this study, six extracts of Arabis carduchorum prepared from solvents of varying polarity (water, methanol, ethyl acetate, dichloromethane, and n-hexane) were investigated for their chemical profiles and total phenolic and flavonoid contents (TPC/TFC) using HPLC-MS/MS and spectrophotometric/colorimetric assays, respectively, along with the assessment of their antioxidant and enzyme inhibitory effects. In general, the polar extracts (methanol, water, and infusion) showed higher TPC/TFC than the other extracts (range: 13.73-26.62 mg GAE/g; 2.66-52.95 mg RE/g, respectively). The total antioxidant capacity of the polar extracts ranged from 0.90-1.85 mmol TE/g in phosphomolybdenum assay, while the free radical scavenging potential ranged from 4.36-32.13 mg TE/g and 12.58-67.73 mg TE/g in DPPH and ABTS assays, respectively. While the water and infuse extract inhibited only butyrylcholinesterase (2.68 and 2.39 mg GALAE/g, respectively), the other extracts were found to inhibit both acetyl- and butyryl-cholinesterases (0.96-2.73 mg GALAE/g and 1.86-5.11 mg GALAE/g, respectively). On the contrary, all extracts exhibited anti-tyrosinase (40.24-59.22 mg KAE/g) and anti-amylase (0.09-0.63 mmol ACAE/g) activities. Overall, this study highlighted the effect of solvent polarity on the extraction of bioactive compounds and the biological properties of the extracts of A. carduchorum; hence, the results obtained could be used to guide optimum extraction in future studies. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Mdpi | en_US |
dc.relation.ispartof | Applied Sciences-Basel | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Accumulation | En_Us |
dc.subject | Alpina | En_Us |
dc.subject | Seeds | En_Us |
dc.subject | Arabis carduchorum | en_US |
dc.subject | phenolics | en_US |
dc.subject | flavonoids | en_US |
dc.subject | HPLC-MS | en_US |
dc.subject | MS | en_US |
dc.subject | solvent polarity | en_US |
dc.subject | antioxidant | en_US |
dc.subject | enzyme inhibition | en_US |
dc.title | Antioxidant and Enzyme Inhibitory Properties, and HPLC-MS/MS Profiles of Different Extracts of Arabis carduchorum Boiss.: An Endemic Plant to Turkey | en_US |
dc.type | article | en_US |
dc.authorid | Çakılcıoğlu, Uğur/0000-0002-3627-3604 | |
dc.authorid | Uba, Abdullahi Ibrahim/0000-0002-0853-108X | |
dc.authorid | Sagratini, Gianni/0000-0001-6231-8709 | |
dc.authorid | Hasan, Mohammad Mehedi/0000-0002-3871-889X | |
dc.authorid | Selvi, Selami/0000-0002-9959-6945 | |
dc.authorid | Angeloni, Simone/0000-0001-6571-2242 | |
dc.authorid | Jugreet, Bibi Sharmeen/0000-0003-1391-5982 | |
dc.identifier.issue | 13 | en_US |
dc.identifier.volume | 12 | en_US |
dc.department | N/A | en_US |
dc.identifier.wos | WOS:000825601800001 | en_US |
dc.identifier.doi | 10.3390/app12136561 | en_US |
dc.identifier.scopus | 2-s2.0-85133420639 | en_US |
dc.institutionauthor | N/A | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorwosid | Çakılcıoğlu, Uğur/AAE-4939-2020 | |
dc.authorwosid | Uba, Abdullahi Ibrahim/P-3971-2019 | |
dc.authorwosid | Sagratini, Gianni/A-2264-2015 | |
dc.authorwosid | Hasan, Mohammad Mehedi/AAQ-2695-2021 | |
dc.authorwosid | Selvi, Selami/E-9561-2019 | |
dc.authorwosid | Angeloni, Simone/AAN-2833-2020 | |
dc.authorwosid | montesano, domenico/O-2391-2018 | |
dc.khas | 20231019-WoS | en_US |