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Toplam kayıt 3535, listelenen: 1-20
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Diltiazemin internal torasik arter kan akımı üzerine etkisi
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Yayıncı ve Tarih:(1996)Bir kalsiyum antagonist! olan diltiazemin koroner arter cerrahisinde internal torasik arter (İTA) akımı üzerindeki etkisini incelemek üzere 60 olgu üzerinde yapılan çalışmada, 30 olguya peroperatif 0.1 mg/kg/saat - 0.3 mg /kg / saat arasında değişen dozlarda diltiazem perfüzyonu başlandı ve 24 saat devam edildi (Grup 1). Diğer 30 olguya (Grup 2) diltiazem verilmedi. Yapılan ölçümlerde İTA kan akımı Grup Vde 110 ± 5 ml/dk, Grup 2'de 70 ± 7 mi/ dk bulundu (p < 0.05). Grup 2'deki olgulara İTA içine ...
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Ekmek mayası (saccharomyces cerevisiae) yardımı ile L-3,4- dihitroksifenil alanin (L-dopa) için yeni bir sentez yöntemi
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Yayıncı ve Tarih:(TUBITAK Scientific & Technical Research Council Turkey, 1997)Ekmek mayası (saccharomyces cerevisiae) kolay ve ucuz bulunan bir reaktif olmasına karşın, organik kimyada yaptığı tepkimeler hem ilginç hem de diğer sentez yöntemleri ile yapılması ya imkansız ya da çok zordur. Bu amaçla klasik organik sentez yöntemleri ve maya kullanılarak daha önce sentezi bu yolla denenmeyen, anti parkinson ilacı L-3,4-Dihidroksifenilalanin'in sentezine yönelik ikisi orjinal dört önemli substurat hazırlanacak ve bu substratlar üzerinde bulunan karbon karbon çift bağı ekmek ...
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Sağlıklı gönüllülerde geri dönüşlü MAO inhibitörü moklobemidin dikkat öncesi süreçler ve işitsel duysal belleğe etkileri
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Yayıncı ve Tarih:(1999)Sekiz sağlıklı gönüllü üzerinde geri dönüşlü monoamin oksidaz inhibitörü moklobemidin, dikkat öncesi beyin süreçleri ve işitsel belleği yansıtan olaya ilişkin potansiyel bileşeni olan mismatch negatifliği (mismatch negativity, MMN) üzerine akut etkileri araştırıldı. Yöntem: İki ayrı edilgen oddbal düzeneğinde, bir saniye uyaranlar arası sürelerde (UAS), kısa (50 ms) ve uzun (500 ms) süreli işitsel uyaranlara karşı olaya ilişkin potansiyeller kaydedildi. Deneklerden kendi seçtikleri bir kitabı ...
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Effect of low-dose methyl prednisolone on serum cytokine levels following extracorporeal circulation
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Yayıncı ve Tarih:(Arnold Hodder Headline Plc., 1999)The systemic inflammatory response to cardiopulmonary bypass (CPB) is associated with increased production of cytokines. This systemic inflammatory response characterized by the activation of interleukin-6 (IL-6) and interleukin-8 (IL-8) during and after CPB is well documented. A prospective randomized double-blind study was performed so as to understand the effects of low-dose methyl prednisolone sodium succinate (MPSS) on the circulating levels of serum cytokines and clinical outcome. Twenty ...
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Aortanın ileri derecede aterosklerozunda koroner arter cerrahisi
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Yayıncı ve Tarih:(1999)Açık kalp cerrahisinde tekniklerin ilerlemesine rağmen nörolojik komplikasyonların görülme sıklığı azalmamıştır ve inme (stroke) morbidite ve mortaliteyi önemli ölçüde artırmaktadır. Bu yazıda çıkan aortada ileri derecede kalsifikasyon bulunan vakalarda hipotermik fibrilasyon tekniği kullanılarak aortaya dokunulmadan ve kross klemp konulmadan yapılan koroner by-pass ameliyatları anlatıldı. 2 yıl içinde aortada ileri derecede kalsifikasyon bulunan 23 olguda bu teknik kullanıldı. Yaş ortalaması 65 ...
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VLSI implementation of GRBF (Gaussian Radial Basis Function) networks
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Yayıncı ve Tarih:(IEEE, 2000)A GRBF network is designed for VLSI implementation. Building blocks of the network consist mainly of analog circuits: op-amp multiplier multiplying DAC (digital to analog converter) floating resistor summer and exponentiator. Parameters of the network (center width of the Gaussian function and output layer weights) are represented digitally for convenient interfacing. It is shown that individual GRBF units allow independent tuning of center width and amplitude. Several network structures are ...
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Malign plevral sıvıların tanısında CYFRA 21-1, CA 19-9, CA-125 ve mutant p53 düzeylerinin değeri
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Yayıncı ve Tarih:(2000)Plevral sıvıların ayırıcı tanısında tümör belirleyicilerinin rolü henüz tam olarak tanımlanamamıştır. Bu çalışmada malign plevral sıvı tanısına katkılarını araştırmak amacıyla sitokeratin 19 fragmanı olan CYFRA 21-1, CA 19-9, CA-125 ve tümör baskılayıcı genlerden p53'ün mutant form ürünü düzeyleri malign plevral sıvılarda (n=20) kantitatif olarak ölçüldü. Bu değerler benign plevral sıvılardaki düzeyler (n=10) ile karşılaştırıldı. CYFRA 21-1 konsantrasyonları katı-faz sandviç immunoradyometrik ölçüm ...
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Facial autologous soft-tissue contouring by adjunction of tissue cocktail injection (micrograft and minigraft mixture of dermis, fascia, and fat)
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Yayıncı ve Tarih:(2000)Facial aging is both a physiologic and anatomic process characterized by changes in the skin and supporting tissues. The aging process produces an outer envelope that gradually expands while its contents gradually involute and the underlying structure weakens. This process results in an excess of skin that tends to create folds, grooves, and deepening furrows. Contour augmentation and filling depressions with autologous tissue or heterogeneous materials are widely used in face rejuvenation as an ...
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Arteriovenöz fistüllerin erken dönem açıklığının venöz sistem basıncının ölçümü ile tayini (Arteriovenöz fistülün arteryel ve venöz sistem basınçlarının analizi)
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Yayıncı ve Tarih:(2000)Kronik böbrek yetersizliğindeki hastalara açılan arteriovenöz şantların erken dönem açıklık oranları birçok faktörden etkilenir. Bu faktörlerin biri de venöz sistemdeki darlık ve tıkanıklıklardır. Bu çalışmanın amacı venöz sistem darlıklarının arteriovenöz fistüllere olan etkisini venöz sistem basıncını ölçerek ortaya koymaktır. İ.Ü İstanbul Tıp Fakültesi Göğüs, Kalp ve Damar Cerrahisi ABD'nda 1997 yılında yapılan 410 arteriovenöz fistülden yaş, cinsiyet ve primer böbrek hastalığı farklılıklarını ...
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Going against the national cultural grain: a longitudinal case study of organizational culture change in Turkish higher education
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Yayıncı ve Tarih:(Carfax Publishing, 2000)This paper presents results of a longitudinal case study inquiry into the measurement of organizational culture change through the implementation of total quality management (TQM) concepts in a higher education context. The inquiry deals with the relationship between national culture and the company corporate culture the consequences of manager style change for TQM implementation and how culture change can be measured adequately. The results are achieved by the utilization of external (quantitative) ...
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Association of lipoprotein(a) concentration and apo(a) isoform size with restenosis after percutaneous transluminal coronary angioplasty
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Yayıncı ve Tarih:(Springer Verlag, 2000)Lp(a) is a unique class of lipoprotein particles that exhibits a considerable size heterogeneity resulting from the size polymorphism of apo(a) its unique protein component. An elevated level of Lp(a) in plasma has been proposed to be a risk factor for premature development of coronary artery disease. To evaluate the relationship between Lp(a) concentration and apo(a) isoform size with restenosis after percutaneous transluminal coronary angioplasty Lp(a) levels and apo(a) phenotypes were determined ...
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Does different orientation of the Medtronic Hall tilting disc valve in the aortic position effect transvalvuler pressure gradients?
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Yayıncı ve Tarih:(Medimond Srl, 2000)The effect of valve orientation during aortic valve replacement (AVR) with the Medtronic Hall (MH) tilting disc valve on transvalvuler pressure gradients was evaluated. 30 patients (pts) undergoing isolated AVR received a MH which was oriented so that the greater opening of the valve faced the non coronary aortic sinus. There were 12 male and 8 female pts in this group with a mean age of 59 +/- 5.2 years. An echocardiographic examination was performed 6 days after the operation and resting ...
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Use of octopus 2 stabilization system for off-pump coronary artery bypass grafting
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Yayıncı ve Tarih:(Medimond Srl, 2000)The early results of 126 off pump CABG procedures performed through a median sternotomy incision (OPCAB) during a period of 18 months were evaluated. The mean age was 69+/-4.3 years. There were 80 male and 46 female patients. Emergency cases and reoperations were not included. A total of 268 anatomosis were performed with a mean number of 2.12 anastomosis Per patient. Conduits used were: LITA (100%) RITA (11.1%) GSV in (84%) and radial artery in (31%) of cases. In 72% of the cases off pump surgery ...
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Intraoperative thermal coronary angiography: quality control
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Yayıncı ve Tarih:(Medimond Srl, 2000)Per operative coronary angiography has always been desired by coronary surgeons. Direct coronary angiographic imaging is not practical since needs contrast injection requires radiation and excessive technology with experienced staff which adds more expenses. Thermal angiography device IVA-2000 (OPGAL) is started to be used in our coronary bypass operations as a routine procedure. Thermal imaging provides an effective and real time coronary angiograms which provides very clear coronary angiograms ...
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In situ split costal cartilage graft harvesting through a small incision using a gouge
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Yayıncı ve Tarih:(Lippincott Williams & Wilkins, 2000)A costal cartilage graft is one of the most useful materials in reconstructive plastic surgery. In this article a technique of in situ split costal cartilage graft harvesting through a small incision (2 to 3 cm) using a gouge is described. The technique used has many advantages: it is a simple technique is easy to learn and can be performed quickly through a small incision. By avoiding complete costal cartilage graft harvesting the associated potential complications such as pleural perforation ...
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Presence and localization of connexins 43 and 26 in cell cultures derived from myometrial tissues from nonpregnant and pregnant women and from leiomyomas
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Yayıncı ve Tarih:(Mosby-Elsevier, 2000)OBJECTIVE: Our objective was to study the appearance and distribution of connexins 43 and 26 in various human myometrial cell cultures. STUDY DESIGN: Scrape loading Western blotting and immunohistochemical techniques were applied to cultured cells derived from myometrial tissues obtained from nonpregnant and pregnant women (upper and tower uterine segments) and from leiomyomas (tumor and analogous myometrial tissues). RESULTS: Scrape loading revealed the presence or metabolic coupling in all ...
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A synthesis tool for the multiplierless realization of FIR-based multirate DSP systems
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Yayıncı ve Tarih:(IEEE, 2000)In this study a synthesis tool using a novel multirate folding technique which handles each FIR filter in a multirate DSP system as a single node is developed. A new architecture is presented for the multiplierless realization of a fold of multirate FIR filters. This synthesizer fully exploits the redundancies (i.e. `idle' and `missing' cycles) and common terms in multirate systems without sacrificing from overall system quality to produce multiplierless multirate systems. It also enables the usage ...
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Off-pump coronary artery bypass grafting with use of the octopus 2 stabilization system
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Yayıncı ve Tarih:(2000)Background: The treatment of coronary artery disease has evolved rapidly over the last two decades. The gold standard of surgical revascularization, the on-pump coronary artery bypass graft, has been challenged by the development of percutaneous transluminal coronary angioplasty. Our experience with the alternative of the off-pump ("beating heart") coronary artery bypass (OPCAB) technique during a period of 18 months suggests that OPCAB avoids the complications of cardiopulmonary bypass and offers ...
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Primary epiploic appendagitis CT manifestations
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Yayıncı ve Tarih:(Elsevier Science Inc, 2000)Inflammation of an epiploic appendage is considered to be a rare cause of acute abdomen. Recently it has been reported that typical computed tomography (CT) findings of primary epiploic appendagitis (PEA) provide a definitive diagnosis in most of the cases. However since these papers are only few they are easily overlooked by the practicing radiologists. Our purpose is to add four new cases to the existing literature and to perform a review of the literature. (C) 2001 Elsevier Science Inc. All ...
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The use of the 5-HT3-receptor antagonist ondansetron for the treatment of postcardiotomy delirium
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Yayıncı ve Tarih:(W.B. Saunders Co Ltd, 2000)Objective:To evaluate the effect of the 5-HT3-receptor antagonist ondansetron in patients with postcardiotomy delirium. Design: Prospective study. Setting: University hospital. Participants: Thirty-five patients who had undergone coronary artery bypass graft surgery. Interventions: Thirty-five patients 23 men and 12 women who developed delirium in the intensive care unit after coronary artery bypass graft surgery were included. Mean patient age was 51.3 years (range 36 to 79 years). A mental status ...