Browsing by Author "Bulutcu, Füsun S."
Now showing items 1-4 of 4
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Does normoxemic cardiopulmonary bypass prevent myocardial reoxygenation injury in cyanotic children?
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Publisher and Date:(W.B. Saunders Co Ltd, 2002)Objective: To evaluate whether the deleterious effect of cardiopulmonary bypass (CPB) can be prevented by controlling PaO2 in cyanotic children. Design: Prospective randomized clinical study. Setting: Single university hospital. Participants: Pediatric patients undergoing cardiac surgery for repair of congenital heart disease (n = 24). Interventions: Patients were randomly allocated into 3 groups. Patients in the acyanotic group (group I n = 10) had CPB initiated at a fraction of inspired oxygen ...
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The involvement of nitric oxide in the analgesic effects of ketamine
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Publisher and Date:(Pergamon-Elsevier Science Ltd, 2002)We investigated the contribution of NO-cyclic GMP (cGMP) pathway to the antinociceptive effects of ketamine in mice by using the nitric oxide synthase inhibitor nitro(g)-L-arginine methyl ester (L-NAME). Intraperitoneal (i.p.) (1 5 or 10 mg/kg) or intrathecal (i.th.) (10 30 or 60 mug/mouse) administration of ketamine produced dose-dependent antinociceptive effects in the acetic acid-induced writhing and formalin tests but not in the tail-flick nor in hot-plate tests. pretreatment of mice with ...
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Which anesthetic agent alters the hemodynamic status during pediatric catheterization? Comparison of propofol versus ketamine
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Publisher and Date:(W.B. Saunders Co Ltd, 2003)Objective: To compare the effects of propofol and ketamine on systemic and pulmonary circulations in pediatric patients scheduled for elective cardiac catheterization. Design: Prospective randomized and blinded. Setting: University hospital. Participants: Children (n = 41) undergoing cardiac catheterization. Interventions: All children were premedicated with oral midazolam 60 minutes before the procedure. Patients were separated into 3 groups according to shunts diagnosed by transthoracic ...
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Which may be effective to reduce blood loss after cardiac operations in cyanotic children: tranexamic acid aprotinin or a combination?
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Publisher and Date:(Blackwell Publishing Ltd, 2005)Background: Children with cyanotic heart disease undergoing cardiac surgery in which cardiopulmonary bypass is used are at increased risk of postoperative bleeding. In this study the authors investigated the possibility of reducing postoperative blood loss by using aprotinin and tranexamic acid alone or a combination of these two agents. Methods: In a prospective randomized blind study 100 children undergoing cardiac surgery were investigated. In group 1 (n = 25) patients acted as the control and ...
