Browsing by Author "Ermutlu, Numan"
Now showing items 1-3 of 3
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Cognitive impairment in amyotrophic lateral sclerosis: evidence from neuropsychological investigation and event-related potentials
Authors:Hanagasi, Hasmet A.; Gurvit, I. Hakan; Ermutlu, Numan; Kaptanoğlu, Gulustu; Karamürsel, Sacit; Idrisoğlu, Halil A.; Emre, Murat; Demiralp, Tamer
Publisher and Date:(Elsevier Science Bv, 2002)The presence of subclinical cognitive impairment in patients with amyotrophic lateral sclerosis (ALS) is investigated using neuropsychological assessment and event-related potential recordings (ERP). An extensive battery of neuropsychological tests assessing the domains of attention memory language visuo-spatial and executive functions were administered to 20 non-demented patients with sporadic ALS and 13 age- and education-matched healthy control subjects. Mismatch negativity (MMN) P3b P3a (novelty ...
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Effects of cold stress on early and late stimulus gating
Authors:Ermutlu, Numan; Karamürsel, Sacit; Uğur, Engin H.; Şentürk, Lerzan; Gökhan, Nuran
Publisher and Date:(Elsevier Ireland Ltd., 2005)The P50 component of the event-related potential (ERP) mainly reflects early pre-attentional processing. Along with P50 the N100 component and mismatch negativity (MMN) were postulated to represent a complex multistage and multi-component gating system. If some variable threshold or gating is exceeded by the MMN signal the MMN is often followed by a relatively sharp fronto-central positive wave the P3a component which reflects an attentional switch to an environmental change. The P50 was shown to ...
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Sağlıklı gönüllülerde geri dönüşlü MAO inhibitörü moklobemidin dikkat öncesi süreçler ve işitsel duysal belleğe etkileri
Sekiz sağlıklı gönüllü üzerinde geri dönüşlü monoamin oksidaz inhibitörü moklobemidin, dikkat öncesi beyin süreçleri ve işitsel belleği yansıtan olaya ilişkin potansiyel bileşeni olan mismatch negatifliği (mismatch negativity, MMN) üzerine akut etkileri araştırıldı. Yöntem: İki ayrı edilgen oddbal düzeneğinde, bir saniye uyaranlar arası sürelerde (UAS), kısa (50 ms) ve uzun (500 ms) süreli işitsel uyaranlara karşı olaya ilişkin potansiyeller kaydedildi. Deneklerden kendi seçtikleri bir kitabı ...