Browsing by Author "Günay, Demet"
Now showing items 1-8 of 8
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11 beta-HSD type 1 is responsible for low plasma hdl-cholesterol and abdominal obesity in metabolic syndrome patients
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Publisher and Date:(Blackwell Publishing Ltd, 2006)
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Acylation stimulating protein and complement c3 mRNA expression in metabolic syndrome
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Publisher and Date:(Blackwell Publishing Ltd, 2006)
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Ateroskleroz gelişmiş metabolik sendrom tedavisinde metformin ve meglitinide analogları
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Publisher and Date:(2003)Bilimsel çalışmalar, prandiyal ve postprandiyal hiperglisemi ve hiperinsülinemi'nin iskemik kalp hastalığını ağırlaştırıcı rol oynadığını, bu sebeple, özellikle tedaviye dirençli ve aterosklerotik kalp 'hastalığı île birlikte bulunan metabolik sendrom vakalarında metformin ve meglitinide kombinasyonunun gerekli olduğunu göstermektedir. Bu çalışmada metformin ve sülfonilüre bileşikleri ile hiperglisemi ve hiperinsülinemi tablosunun düzeltilemediği ateroskleroz komponenti ağırlık kazanmış metabolik ...
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Effect of abdominal obesity on insulin resistance and the components of the metabolic syndrome: Evidence supporting obesity as the central feature
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Publisher and Date:(F D-Communications Inc., 2003)Background: Metabolic syndrome includes abdominal obesity diabetes type 2 hypertension dyslipidemia derangements of fibrinolysis and atherosclerosis. Since abdominal obesity is one of the major components of the insulin resistance syndrome (IRS) an attempt was made to evaluate the interrelationships between the magnitude of obesity and the components of the syndrome. Methods: A cross-sectional study of 123 subjects with type 2 diabetes of whom M were normal body weight and 92 had varying degrees ...
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Genetic variations of the apolipoprotein B gene in Turkish patients with coronary artery disease
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Publisher and Date:(Taylor & Francis Ltd, 2005)Background: The results of studies that clarify the association of genetic markers at the apolipoprotein B (apo B) gene (EcoRI and XbaI polymorphisms) with coronary artery disease (CAD) are not consistent and suggest that the effect is context dependent (dependent on ethnicity and sex). The present study represents the first investigation of the apo B gene polymorphisms in Turkish patients with CAD and their influence on lipid levels. Aim: The study investigated the association of apo B gene EcoRI ...
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Lipoprotein lipase gene polymorphism and lipid profile in coronary artery disease
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Publisher and Date:(COLL AMER PATHOLOGISTS, 2004)Context.-Lipoprotein lipase (LPL) plays a central role in lipid metabolism hydrolyzing triglyceride in chylomicrons and very-low-density lipoproteins. The PvuII polymorphic variant of LPL gene is common and might affect risk of coronary artery disease (CAD). Objective.-Our aim was to determine whether LPL-PvuII polymorphism can be considered to be an independent risk factor or a predictor for CAD in Turkish subjects. Design.-We used polymerase chain reaction and restriction enzyme digestion to ...
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The interrelationship between insulin secretion and action in Type 2 diabetes mellitus with different degrees of obesity: Evidence supporting central obesity
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Publisher and Date:(Editrice Kurtis S R L, 2003)This paper investigates the relative role of the impairment of insulin secretion and action in the pathogenesis of Type 2 diabetes mellitus (T2DM). The parameters indicating insulin secretion and action were calculated from the data obtained during oral glucose tolerance test (OGTT) in 156 age- and sex-matched T2DM patients divided in 4 groups according to their body mass index (BMI I=20.0-24.9 II=25.0-29.9 III=30.0-39.9 and IV>40.0 kg/m(2)). After obtaining baseline biomedical parameters (plasma ...
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The role of FABP4 gene expression in metabolic syndrome patients with previous myocardial infarction
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Publisher and Date:(Wiley, 2006)
