Browsing by Author "Pomplun, Marc"
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Accurate Refinement Of Docked Protein Complexes Using Evolutionary Information And Deep Learning
Authors:Akbal-Delibas, Bahar; Farhoodi, Roshanak; Pomplun, Marc; Haspel, Nurit
Publisher and Date:(Imperıal College Press, 2016)One of the major challenges for protein docking methods is to accurately discriminate native-like structures from false positives. Docking methods are often inaccurate and the results have to be refined and re-ranked to obtain native-like complexes and remove outliers. In a previous work we introduced AccuRefiner a machine learning based tool for refining protein-protein complexes. Given a docked complex the refinement tool produces a small set of refined versions of the input complex with lower ...