Istıf, Emın

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Istıf, Emın
E.,Istıf
E. Istıf
Emın, Istıf
Istif, Emin
E.,Istif
E. Istif
Emin, Istif
Job Title
Dr. Öğr. Üyesi
Email Address
Emın.ıstıf@khas.edu.tr
Main Affiliation
Molecular Biology and Genetics
Status
Former Staff
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Scholarly Output

11

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9

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0

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Now showing 1 - 2 of 2
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    Article
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    Paper Integrated Microfluidic Contact Lens for Colorimetric Glucose Detection
    (Royal Soc Chemistry, 2024) Isgor, Pelin Kubra; Istıf, Emın; Abbasiasl, Taher; Das, Ritu; Istif, Emin; Yener, Umut Can; Beker, Levent
    Contact lenses offer a simple, cost-effective, and non-invasive method for in situ real-time analysis of various biomarkers. Electro-chemical sensors are integrated into contact lenses for analysis of various biomarkers. However, they suffer from rigid electronic components and connections, leading to eye irritation and biomarker concentration deviation. Here, a flexible and microfluidic integrated paper-based contact lens for colorimetric analysis of glucose was implemented. Facilitating a three-dimensional (3D) printer for lens fabrication eliminates cumbersome cleanroom processes and provides a simple, batch compatible process. Due to the capillary force of the filter paper, the sample was routed to detection chambers inside microchannels, and it allowed further colorimetric detection. The paper-embedded microfluidic contact lens successfully detects glucose down to 2 mM within similar to 10 s. The small dimension of the microfluidic system enables detection of glucose levels as low as 5 mu l. The results show the potential of the presented approach to analyze glucose concentration in a rapid manner. It is demonstrated that the fabricated contact lens can successfully detect glucose levels of diabetic patients. Contact lenses offer a simple, cost-effective, and non-invasive method for in situ real-time analysis of various biomarkers.
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    Article
    Citation - WoS: 0
    Citation - Scopus: 0
    Near-Infrared Triggered Degradation for Transient Electronics
    (Amer Chemical Soc, 2024) Istıf, Emın; Ali, Mohsin; Ozuaciksoz, Elif Yaren; Morova, Yagiz; Beker, Levent
    Electronics that disintegrate after stable operation present exciting opportunities for niche medical implant and consumer electronics applications. The disintegration of these devices can be initiated due to their medium conditions or triggered by external stimuli, which enables on-demand transition. An external stimulation method that can penetrate deep inside the body could revolutionize the use of transient electronics as implantable medical devices (IMDs), eliminating the need for secondary surgery to remove the IMDs. We report near-infrared (NIR) light-triggered transition of metastable cyclic poly-(phthalaldehyde) (cPPA) polymers. The transition of the encapsulation layer is achieved through the conversion of NIR light to heat, facilitated by bioresorbable metals, such as molybdenum (Mo). We reported a rapid degradation of cPPA encapsulation layer about 1 min, and the rate of degradation can be controlled by laser power and exposure time. This study offers a new approach for light triggerable transient electronics for IMDs due to the deep penetration depth of NIR light through to organs and tissues.