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Now showing items 641-660 of 3145
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Design, synthesis, molecular modeling, and bioactivity evaluation of 1,10-phenanthroline and prodigiosin (Ps) derivatives and their Copper(I) complexes against mTOR and HDAC enzymes as highly potent and effective new anticancer therapeutic drugs
(Frontiers Media Sa, 2022)Breast cancer is the second type of cancer with a high probability of brain metastasis and has always been one of the main problems of breast cancer research due to the lack of effective treatment methods. Demand for ... -
Designing of an enterprise product innovation system for companies
(Kadir Has Üniversitesi, 2018)Today, innovation is the most decisive factor for companies to grow and gain competitive edge in the market. In particular, firms support a product innovation policy in order to be permanent in the market. Product ... -
Designing of multi-targeted molecules using combination of molecular screening and in silico drug cardiotoxicity prediction approaches
(Elsevier Science Inc, 2014)We have previously investigated and reported a set of phenol- and indole-based derivatives at the binding pockets of carbonic anhydrase isoenzymes using in silico and in vitro analyses. In this study we extended our analysis ... -
Designing of selective and potent inhibitors against histone deacetylase enzymes (HDAC6 VE HDAC10) via in silico screening and molecular modeling techniques for the treatment of cancer
(Kadir Has Üniversitesi, 2021)HDACs are the class of enzymes that are involved in the process of cancer development by removing the acetyl groups from histone protein, inducing chromatin condensation and in this way regulating the expression of tumor ... -
The despotic imperative: From Hiero to the circle
(Duke University Press, 2019)The article thematizes the actuality of despotism through a double reading of Xenophon’s Hiero and Dave Eggers’s Circle. A key text on despotism, Hiero is interesting to reconsider in a contemporary context because of its ... -
Detached eddy simulation of shallow mixing layer development between parallel streams
(Elsevier Science Bv, 2015)Results of a high resolution Detached Eddy Simulation (DES) are used to characterize the evolution of a shallow mixing layer developing between two parallel streams in a long open channel with a smooth flat bed and medium ... -
Detecting structural changes using wavelets
(Academic Press Inc Elsevier Science, 2015)We propose a powerful wavelet method to identify structural breaks in the mean of a process. If there is a structural change in the mean the sum of the squared scaling coefficients absorbs more variation leading to unequal ... -
Detection of Click Spamming in Mobile Advertising
(Springer Science and Business Media B.V., 2020)Most of the marketing expenditures in mobile advertising are conducted through real-time bidding (RTB) marketplaces, in which ad spaces of the sellers (publishers) are auctioned for the impression of the buyers’ (advertisers) ... -
Detection of fraudulent activities in mobile display advertising
(Kadir Has Üniversitesi, 2017)Most of the marketing expenditures in mobile advertising are conducted through realtime bidding (RTB) marketplaces in which ad spaces of the sellers (publishers) are auctioned for the impression of the buyers’ (advertisers) ... -
Detection of interdependent multiband systems for cognitive radios and ultra-wideband systems
(Kadir Has Üniversitesi, 2012)As a result of advances in the wireless technology new systems have been proposed and hence more frequency bands are occupied in the spectrum. Therefore the number ofavailable frequency bands for future wireless communication ... -
Detection of interdependent primary systems using wideband cognitive radios
(Elsevier GMBH Urban & Fischer Verlag, 2013)Cognitive radios (CRs) may be sharing multiple frequency bands with primary systems if the CR is a wideband or an ultra wideband (UWB) system. In that case the CR should ensure all the coexisting primary systems in these ... -
Detection of jointly active primary systems
(IEEE, 2012)Recent studies in cognitive radios consider the detection of multiple bands for a better utilization of the spectrum. If the cognitive radio (CR) is an ultra wideband (UWB) or a wideband system then the CR should ensure ... -
Detection of Multiple Primary Systems Using DAA UWB-IRs
(IEEE, 2009)Underlay ultra wideband (UWB) systems have to be able to detect the presence of primary systems operating in the same band for detect-and-avoid (DAA) operation. In this paper the performances of joint and independent ... -
Detection of Trojans in integrated circuits
(IEEE, 2012)This paper presents several signal processing approaches in Trojan detection problem in very large scale integrated circuits. Specifically wavelet transforms spectrograms and neural networks are used to analyze power ... -
Determinants of bank lending 'Evidence from BRICS countries'
(Kadir Has Üniversitesi, 2023-01)This thesis aims to investigate the determinants of bank lending for the countries forming BRICS, namely Brazil, Russia, India, China, and South Africa. The empirical analysis is performed using a sample of 130 listed ... -
Determinants of corporate cash holdings: Firm level evidence from emerging markets
(Springer, 2017)The objective of this chapter is to investigate the factors affecting corporate cash holdings in five emerging markets namely Brazil Indonesia Mexico Russia and Turkey. The sample consists of 1991 firms listed on the major ... -
Determinants of Currency Crises in Turkey Some Empirical Evidence
(M.E Sharpe Inc., 2010)Currency crises have become a serious threat for developing countries especially since the financial deregulation process and the collapse of the Bretton Woods system. In the past two decades Turkey has experienced two ... -
Determinants of investment in the manufacturing sector in Turkey
(Kadir Has Üniversitesi, 2017)This dissertation focuses on the determinants of investment in Turkish manufacturing sector. it gives a detailed framework and complementary analysis of the determinants of investment in Turkish manufacturing sector. First ... -
Determinants of Investment in Turkey: A Firm-Level Investigation
(Routledge Journals Taylor & Francis Ltd, 2019)In this article we analyze the financing constraints-investment link for the case of Turkey between 1996 and 2013. As different from the existing studies on Turkey we use a more comprehensive data set that includes both ... -
Determinants of Saving-Borrowing Decisions and Financial Inclusion in a High Middle Income Country: The Turkish Case
(Routledge Journals Taylor & Francis Ltd, 2016)We use a representative survey of the Turkish household sector and investigate factors impinging on saving-borrowing behavior. We run four probit regressions to elucidate (i) the saving decision (ii) asset choice or portfolio ...