Browsing by Author "Duman, Belgin Süsleyici"
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Acylation stimulating protein and complement c3 mRNA expression in metabolic syndrome
Duman, Belgin Süsleyici; Çiftçi, C.; Atalar, Fatmahan; Demirkan, A.; Vural, B.; Çağatay, Penbe; Günay, Demet; Sağbaş, E.; Akpınar, Belhhan; Özbek, U.; Büyükdevrim, Ahmet Sevim (Blackwell Publishing Ltd, 2006)[Abstract Not Available] -
Apolipoprotein B gene variants are involved in the determination of blood glucose and lipid levels in patients with non-insulin dependent diabetes mellitus
Duman, Belgin Süsleyici; Öztürk, Melek; Yilmazer, Selma; Çağatay, Penbe; Hatemi, Hüsrev (Wiley, 2006)We have examined the frequency of the EcoRI XbaI and MspI RFLPs of the apolipoprotein B (apo 13) gene in I 10 type 2 diabetic patients and 9 1 healthy control subjects in order to ascertain whether variation in this gene ... -
Apolipoprotein E polymorphism in Turkish subjects with Type 2 diabetes mellitus: Allele frequency and relation to serum lipid concentrations
Duman, Belgin Süsleyici; Öztürk, Melek; Yilmazer, Selma; Hatemi, Hüsrev (EDITRICE KURTIS S R L, 2004)The role of apolipoprotein E (apoE) genotypes in modulating plasma lipid and apolipoprotein levels was studied in 112 patients with Type 2 diabetes mellitus (T2DM) and 94 healthy individuals. ApoE genotypes were identified ... -
DNA polymorphism of Pvu II site in the lipoprotein lipase gene in patients with non-insulin dependent diabetes mellitus
Duman, Belgin Süsleyici; Öztürk, Melek; Yilmazer, Selma; Çağatay, Penbe; Hatemi, Hüsrev (Wiley, 2005)We studied the effect of variation at the lipoprotein lipase (LPL) gene locus on the susceptibility of individuals with non-insulin dependent diabetes mellitus (NIDDM) in a population of 110 NIDDM patients and 91 controls. ... -
Effect of abdominal obesity on insulin resistance and the components of the metabolic syndrome: Evidence supporting obesity as the central feature
Türkoğlu, Çavlan; Duman, Belgin Süsleyici; Günay, Demet; Çağatay, Penbe; Ozcan, Remzi; Buyukdevrim, Ahmet Sevim (F D-Communications Inc., 2003)Background: Metabolic syndrome includes abdominal obesity diabetes type 2 hypertension dyslipidemia derangements of fibrinolysis and atherosclerosis. Since abdominal obesity is one of the major components of the insulin ... -
Genetic variations of the apolipoprotein B gene in Turkish patients with coronary artery disease
Duman, Belgin Süsleyici; Türkoğlu, Çavlan; Akpınar, Belhhan; Güden, Mustafa; Vertii, Anastassia; Çağatay, Penbe; Günay, Demet; Büyükdevrim, Ahmet Sevim (Taylor & Francis Ltd, 2005)Background: The results of studies that clarify the association of genetic markers at the apolipoprotein B (apo B) gene (EcoRI and XbaI polymorphisms) with coronary artery disease (CAD) are not consistent and suggest that ... -
The interrelationship between insulin secretion and action in Type 2 diabetes mellitus with different degrees of obesity: Evidence supporting central obesity
Duman, Belgin Süsleyici; Türkoğlu, Cengizhan; Günay, Demet; Çağatay, Penbe; Demiroğlu, C; Büyükdevrim, Ahmet Sevim (Editrice Kurtis S R L, 2003)This paper investigates the relative role of the impairment of insulin secretion and action in the pathogenesis of Type 2 diabetes mellitus (T2DM). The parameters indicating insulin secretion and action were calculated ... -
Lipoprotein lipase gene polymorphism and lipid profile in coronary artery disease
Duman, Belgin Süsleyici; Türkoğlu, Caner; Akpinar, Belhhan; Güden, Mustafa; Vertii, Alexey; Dak, Esranur; Çağatay, Tülin; Günay, Demet; Buyukdevrim, Ahmet Sevim (COLL AMER PATHOLOGISTS, 2004)Context.-Lipoprotein lipase (LPL) plays a central role in lipid metabolism hydrolyzing triglyceride in chylomicrons and very-low-density lipoproteins. The PvuII polymorphic variant of LPL gene is common and might affect ... -
Polymorphisms at the ligand binding site of the vitamin D receptor gene and osteomalacia
Ak, Duygu Gezen; Kahraman, Hakkı; Dursun, Erdinç; Duman, Belgin Süsleyici; Erensoy, Nevin; Alagöl, Faruk; Tanakol, Refik; Yilmazer, Selma (Hindawi Ltd, 2005)Vitamin D receptor (VDR) gene polymorphisms have been suggested as possible determinants of bone mineral density (BMD) and calcium metabolism. In this study our aim was to determine whether there is an association between ... -
Protective effects of a calcium channel blocker on apoptosis in thymus of neonatal STZ-diabetic rats
Dağıstanlı, Fatma Kaya; Duman, Belgin Süsleyici; Öztürk M. (Elsevier GMBH Urban & Fischer Verlag, 2005)Streptozotocin (STZ) is known to induce insulin-dependent diabetes in experimental animals. In STZ-induced diabetes atrophy of the thymus is caused by elevated intracellular calcium levels leading to apoptosis. Hyperglycemia ... -
Quantitative expression analysis of glucocorticoid receptor (GcR) gene in metabolic syndrome
Demirkan, A.; Atalar, Fatmahan; Vural, B.; Duman, Belgin Süsleyici; Çiftçi, C.; Günay, Gökhan; Çağatay, Penbe; Sağbas, E.; Akpınar, Belhhan; Özbek, Uğur; Büyükdevrim, Ahmet Sevim (Wiley, 2006)[Abstract Not Available] -
The role of FABP4 gene expression in metabolic syndrome patients with previous myocardial infarction
Vural, B.; Atalar, Fatmahan; Demirkan, A.; Çiftçi, C.; Duman, Belgin Süsleyici; Çağatay, Penbe; Günay, Demet; Sağbaş, E.; Akpınar, Belhhan; Özbek, U.; Büyükdevrim, Ahmet Sevim (Wiley, 2006)[Abstract Not Available] -
Thiols malonaldehyde status in the Turkish and total antioxidant patients with type 2 diabetes mellitus
Duman, Belgin Süsleyici; Öztürk, Melek; Yilmazer, Selma; Hatemi, Hüsrev (Tohoku Univ Medical Press, 2003)Non-insulin-dependent (Type 2) diabetes mellitus (NIDDM) is a risk factor for cardiovascular diseases (CVD). Oxidative stress mechanisms are often reported to be implied in type 2 diabetes mellitus. In order to determine ... -
Vitamin D receptor alleles bone mineral density and turnover in postmenopausal osteoporotic and healthy women
Duman, Belgin Süsleyici; Tanakol, Refik; Erensoy, Nevin; Öztürk, Melek; Yılmazer, Selma (Karger, 2004)Objective: Vitamin D receptor (VDR) gene polymorphisms and bone metabolic markers were investigated as potential genetic markers for osteoporosis in postmenopausal Turkish women. The relationship between their VDR gene ...