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Crystallographic structure versus homology model: a case study of molecular dynamics simulation of human and zebrafish histone deacetylase 10
(Taylor & Francis, 2020)
Histone deacetylase (HDAC) 10 has been implicated in the pathology of various cancers and neurodegenerative disorders, making the discovery of novel inhibitors of the isoform an important endeavor. However, the unavailability ...
Antifungal screening and in silico mechanistic studies of an in-house azole library
(2019)
Systemic Candida infections pose a serious public health problem with high morbidity and mortality. C. albicans is the major pathogen identified in candidiasis; however, non-albicans Candida spp. with antifungal resistance ...
Municipal solid waste management via mathematical modeling: A case study in İstanbul, Turkey
(Elsevier, 2019)
The prominence of managing municipal solid waste (MSW) in an efficient and effective manner is increasing from day to day. In this paper, the solid waste management (SWM) system of İstanbul is analyzed by applying the ...
Synthesis, biological evaluation and molecular docking studies of bis-chalcone derivatives as xanthine oxidase inhibitors and anticancer agents
(Elsevier, 2019)
In this study, a series of B-ring fluoro substituted bis-chalcone derivatives were synthesized by Claisen-Schmidt condensation reactions and evaluated for their ability to inhibit xanthine oxidase (XO) and growth inhibitory ...
The acquisition and use of relative clauses in Turkish-learning children's conversational interactions: a cross-linguistic approach
(Cambridge University Press, 2019)
Using a cross-linguistic approach, we investigated Turkish-speaking children's acquisition and use of relative clauses (RCs) by examining longitudinal child-caregiver interactions and cross-sectional peer conversations. ...
Neo-Weberian historical sociology, the English School and differentiated integration in the E
(Routledge Journals, Taylor & Francıs Ltd, 2020)
This article explores the contributions of Neo-Weberian historical sociology of the state and the English School of International Relations theory to our understanding of differentiated integration in the European Union. ...
Holocene climate forcings and lacustrine regime shifts in the Indian summer monsoon realm
(Wıley, 2020)
Extreme climate events have been identified both in meteorological and long-term proxy records from the Indian summer monsoon (ISM) realm. However, the potential of palaeoclimate data for understanding mechanisms triggering ...
Revisiting the Britain-US-Turkey triangle during the transition from Pax Britannica to Pax Americana (1947-1957)
(Routledge Journals, Taylor & Francıs Ltd, 2020)
This article analyses the triangular relations between Britain, the United States and Turkey in the volatile Middle East and Eastern Mediterranean region at the advent of the Cold War. It examines the political, economic ...
Metamorphic Leaves
(Mıt Press, 2020)
This article introduces an algorithm influenced by Goethe's concept of metamorphosis capable of generating a wide range of parametric leaf forms. Metamorphosis is defined as alternating stages of expansion and contraction ...
Integrated Marketing Communication with the understanding of Public Relations
(Istanbul Univ, 2009)
The dicipline of public relations usually used to be at the secondary importance in marketing communication activities for ages. Promotion stage of marketing mix was predominantly advertising. PR, however, was only an extra ...