Browsing Araştırma Çıktıları | WoS | Scopus | TR-Dizin | PubMed by Department "Fakülteler, Mühendislik ve Doğa Bilimleri Fakültesi, Biyoinformatik ve Genetik Bölümü"
Now showing items 101-120 of 200
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In silico design of novel and highly selective lysine-specific histone demethylase inhibitors
(Scientific Technical Research Council Turkey-Tubitak, 2011)Histone lysine-specific demethylase (LSD1) is involved in a wide range of epigenetic processes and plays important roles in gene silencing DNA transcription DNA replication DNA repair and heterochromatin formation. Its ... -
In silico identification of novel and selective monoamine oxidase B inhibitors
(SPRINGER WIEN, 2013)Monoamine oxidases (MAO) A and B are flavin adenine dinucleotides containing enzymes bound to the mitochondrial outer membranes of the cells of the brain liver intestine and placenta as well as platelets. Recently selective ... -
In Silico Modeling of Dopamine Transporter and Design of Novel Neuroprotective Agents
(Amer Chemical Soc, 2016)[Abstract Not Available] -
In situ steady state fluorescence (SSF) technique to study drying of PAAm hydrogels made of various cross-linker contents
(Elsevier Science, 2009)Drying experiments of polyacrylamide (PAAm) gels were performed using steady-state fluorescence (SSF) spectrometer. Pyranine (P) was introduced as a fluorescence probe and intensity of P from various crosslinker content ... -
Insights into the binding mode of new N-substituted pyrazoline derivatives to MAO-A: docking and quantum chemical calculations
(SPRINGER WIEN, 2013)The binding modes of four N-substituted pyrazoline derivatives as novel MAO-A inhibitory agents were investigated using docking and quantum chemical molecular modelling tools. -
Intermolecular interactions in human HDAC8 crystal structures and the stability of binding modes of co-crystallized inhibitors
(Amer Chemical Soc, 2019)[Abstract Not Available] -
Intrinsic Dynamics and Causality in Correlated Motions Unraveled in Two Distinct Inactive States of Human beta(2)-Adrenergic Receptor
(Amer Chemical Soc, 2019)The alternative inactive state of the human beta(2)-adrenergic receptor originally exposed in molecular dynamics simulations was investigated using various analysis tools to evaluate causality between correlated residue-pair ... -
Investigation of allosteric communication pathways in human beta 2-adrenergic receptor
(Wiley-Blackwell, 2015)[Abstract Not Available] -
Investigation of Allosteric Coupling in Human Beta(2)-Adrenergic Receptor in the Presence of Intracellular Loop 3
(BMC, 2016)Background: This study investigates the allosteric coupling that exists between the intra- and extracellular parts of human beta(2)-adrenergic receptor (beta(2)-AR) in the presence of the intracellular loop 3 (ICL3) which ... -
Investigation of Drying of Poly(N-isoproplacrylamide-co-acrylamide) by Fluorescence Technique
(Wiley-Blackwell, 2013)The steady-state fluorescence technique was performed on drying of various molar percentages of poly(N-isopropylacrylamide-co- acrylamide) [poly(NIPA-co-AAc)] to elucidate the mechanism of temperature-induced phase separation ... -
Investigation of intrinsic dynamics and allosteric coupling in human beta 2-adrenergic receptor
(Springer, 2017)[Abstract Not Available] -
Investigation of PSt-MWCNT concentration on epoxyacrylate photopolymerization and conductivity of polymer films
(Elsevier Science SA, 2013)Photopolymerization kinetics and conductivity changes of epoxyacrylate composites for various loading modified PSt-MWCNT weight fractions changing from 0.0025 to 0.2 wt.% were evaluated by performing photo differential ... -
Kinetic models for the dynamical behavior of polyacrylamide (PAAm)-kappa-carrageenan (kappa C) composite gels
(Springer, 2015)A fluorescence method was employed for studying the drying and swelling of PAAm-kappa C composite gels which were formed from acrylamide (AAm) and N N'- methylenebisacrylamide (BIS) with various kappa-carrageenan (kappa ... -
Level Densities of Heavy Nuclei in the Shell Model Monte Carlo Approach
(EDP Sciences, 2016)Nuclear level densities are necessary input to the Hauser-Feshbach theory of compound nuclear reactions. However the microscopic calculation of level densities in the presence of correlations is a challenging many-body ... -
Ligand-binding affinity of alternative conformers of human beta(2)-adrenergic receptor in the presence of intracellular loop 3 (ICL3) and their potential use in virtual screening studies
(Wiley, 2019)This study investigates the structural distinctiveness of orthosteric ligand-binding sites of several human beta(2) adrenergic receptor (beta(2)-AR) conformations that have been obtained from a set of independent molecular ... -
Mapping the two-component atomic Fermi gas to the nuclear shell-model
(Springer, 2014)The physics of a two-component cold Fermi gas is now frequently addressed in laboratories. Usually this is done for large samples of tens to hundreds of thousands of particles. However it is now possible to produce few-body ... -
A mathematical characterization of the gel point in sol-gel transition
(IOP Publishing Ltd, 2015)We model the sol-gel transition in terms of Susceptible-Infected-Removed (SIR) and Susceptible-Exposed-Infected-Removed (SEIR) models and compare with experimental results. We show, numerically, that the "gel point" described ... -
Mathematical Characterization of Thermo-reversible Phase Transitions of Agarose Gels
(Taylor & Francis Inc, 2018)The thermal phase transition temperatures of high (HMP) and low melting point (LMP) agarose gels were investigated by using UV-vis spectroscopy techniques. Transmitted light intensities from the gel samples with different ... -
Measurement of oxygen diffusion in PS/PNIPAM films using fluorescence quenching
(Taylor & Francis Ltd, 2015)The diffusion of oxygen into pyrene labelled polystyrene (PS) latex/poly(N-isopropylacrylamide) (PNIPAM) composite films (PS/PNIPAM) was studied based on PS content with the use of fluorescence quenching method. Fluorescence ... -
Mechanical properties of graphene oxide-polyacrylamide composites before and after swelling in water
(Springer, 2018)Polyacrylamide (PAAm) hydrogels have been proposed for use as promising biomaterials in biomedical and tissue engineering but their poor mechanical and water-retention properties have hindered their development. Graphene ...