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In silico design of novel and highly selective lysine-specific histone demethylase inhibitors
(Scientific Technical Research Council Turkey-Tubitak, 2011)
Histone lysine-specific demethylase (LSD1) is involved in a wide range of epigenetic processes and plays important roles in gene silencing DNA transcription DNA replication DNA repair and heterochromatin formation. Its ...
Power of inhibition activity screening and 3D molecular modeling approaches in HDAC 8 inhibitor design
(Scientific Technical Research Council Turkey-Tubitak, 2011)
In-vitro inhibition activity screening and in-silico 3D molecular modeling approaches are important tools for design and development of specific histone deacetylase (HDAC) inhibitors. The objective of this study was to ...
Sparsity Preserving Computation for Spectral Projectors
(Amer Inst Physics, 2011)
Several areas of applications such as model order reduction preconditioner design and eigenvalue problems for spectral projectors can be found in the literature. In this paper a fast and sparsity preserving approach for ...
Export Conditions of the Chinese Textile Industry: An Analysis in Comparison with Selected ASEAN Countries
(Sage Publications Ltd, 2010)
This paper provides a comprehensive and disaggregated set of elasticity estimates to date in the face of MFA abolishment. The estimates made here are at a detailed level of disaggregation and should provide researchers ...
Rapidly Time-Varying Channel Estimation for Full-Duplex Amplify-and-Forward One-Way Relay Networks
(IEEE-INST Electrical Electronics Engineers Inc, 2018)
Estimation of both cascaded and residual self-interference (RSI) channels and a new training frame structure are considered for full-duplex (FD) amplify-and-forward (AF) one-way relay networks with rapidly time-varying ...
Short term effects of a low-carbohydrate diet in overweight and obese subjects with low HDL-C levels
(BIOMED CENTRAL LTD, 2010)
Background: The aim of this study was to evaluate short-term effects of a low-carbohydrate diet in overweight and obese subjects with low HDL-C levels. Methods: Overweight (BMI between 25-30 kg/m(2)) or obese (BMI over 30 ...
Turkey's Energy Strategy and the Middle East: Between a Rock and a Hard Place
(Routledge Journals Taylor & Francis Ltd, 2011)
This article examines Turkey's energy relations with the Middle East from a perspective of opportunities and limitations brought about by the structure of Turkey's general energy relations. As Turkish foreign policy and ...
Improving performances of suboptimal greedy iterative biclustering heuristics via localization
(Oxford University Press, 2010)
Motivation: Biclustering gene expression data is the problem of extracting submatrices of genes and conditions exhibiting significant correlation across both the rows and the columns of a data matrix of expression values. ...
Morphotectonic development of the Marmara Region
(Elsevier Science Bv, 2010)
The Marmara Region of northwest Turkey covers the Marmara Sea Basin and the surrounding lands. In the region morphologically different areas may be distinguished. The Marmara Sea Basin is a structural depression. The land ...
Joint Channel Estimation Equalization and Data Detection for OFDM Systems in the Presence of Very High Mobility
(IEEE-INST Electrical Electronics Engineers Inc, 2010)
This paper is concerned with the challenging and timely problem of joint channel estimation equalization and data detection for uplink orthogonal frequency division multiplexing (OFDM) systems in the presence of frequency ...