Browsing Tez Koleksiyonu by Subject "Homology modeling of human HDAC10"
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Targeting cancer epigenetic modifiers: The design of isoform-selective histone deacetylase inhibitors
(Kadir Has Üniversitesi, 2018)Epigenetic alterations are believed to be the common hallmark of human cancers. Histone deacetylase (HDAC) inhibitors have proven to be effective in cancer cases where HDACs are up-regulated. However lack of selectivity ...