Browsing Mühendislik ve Doğa Bilimleri Fakültesi by Publisher "Elsevier Sci Ltd"
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Pharmacophore-based virtual screening for identification of potential selective inhibitors of human histone deacetylase 6
(Elsevier Sci Ltd, 2018)Histone deacetylase (HDAC) 6 plays a role in oncogenic transformation and cancer metastasis via tubulin deacetylation, making it a critical target for anticancer drug design. However, lack of selectivity shown by many of ... -
A 'Regional Energy Hub' for achieving a low-carbon energy transition
(Elsevier Sci Ltd, 2018)The transition to a low-carbon energy economy will remain a cornerstone of national energy policies of countries committed to the climate change accord for decades to come. We think that transmission investment is one key ...