Browsing PubMed İndeksli Yayınlar Koleksiyonu by Type "article"
Now showing items 161-180 of 339
-
Improving performances of suboptimal greedy iterative biclustering heuristics via localization
(Oxford University Press, 2010)Motivation: Biclustering gene expression data is the problem of extracting submatrices of genes and conditions exhibiting significant correlation across both the rows and the columns of a data matrix of expression values. ... -
In silico identification of critical proteins associated with learning process and immune system for Down syndrome
(Public Library Science, 2019)Understanding expression levels of proteins and their interactions is a key factor to diagnose and explain the Down syndrome which can be considered as the most prevalent reason of intellectual disability in human beings. ... -
In silico identification of novel and selective monoamine oxidase B inhibitors
(SPRINGER WIEN, 2013)Monoamine oxidases (MAO) A and B are flavin adenine dinucleotides containing enzymes bound to the mitochondrial outer membranes of the cells of the brain liver intestine and placenta as well as platelets. Recently selective ... -
An In-Depth Study on the Metabolite Profile and Biological Properties of Primula auriculata Extracts: A Fascinating Sparkle on the Way from Nature to Functional Applications
(Mdpi, 2022)The biological activity of the aerial part and rhizomes of Primula auriculata were assessed for the first time. The biological activities (antioxidant properties, enzyme inhibition, and AGE inhibition) as well as the ... -
The in-vivo assessment of Turkish propolis and its nano form on testicular damage induced by cisplatin
(Elsevier, 2021)Objective: Chemotherapeutic drugs, such as cisplatin (CP), which are associated with oxidative stress and apoptosis, may adversely affect the reproductive system. This study tests whether administration of propolis and ... -
Influence of cardiovascular risk factors on the outcome of coronary artery bypass surgery
(Springer Verlag, 2003)Purpose. To assess the impact of gender age and other cardiovascular risk factors on the outcomes of patients undergoing coronary artery bypass grafting (CABG). Methods. A total of 5 067 consecutive patients undergoing ... -
Influence of combined antioxidants against cadmium induced testicular damage
(Elsevier Science Bv, 2006)Acute effects ofcadmium (Cd) and combined antioxidants were evaluated in Sprague-Dawley rat testes. The rats were subdivided into four groups. Cadmium chloride (2 mg/kg day) injected intraperitoneally during 8 days. Vitamin ... -
Insights into the binding mode of new N-substituted pyrazoline derivatives to MAO-A: docking and quantum chemical calculations
(SPRINGER WIEN, 2013)The binding modes of four N-substituted pyrazoline derivatives as novel MAO-A inhibitory agents were investigated using docking and quantum chemical molecular modelling tools. -
An Integrated Molecular Communication System Based on Acoustic Tweezers
(IEEE-Inst Electrical Electronics Engineers Inc, 2023)In this work, a molecular communication link integrated with a micro-electro mechanical system (MEMS) based environment has been designed and simulated. The motivation behind this approach is to explore the possibility of ... -
Inter-trial effects in priming of pop-out: Comparison of computational updating models
(Public Library Science, 2021)In visual search tasks, repeating features or the position of the target results in faster response times. Such inter-trial 'priming' effects occur not just for repetitions from the immediately preceding trial but also ... -
The interrelationship between insulin secretion and action in Type 2 diabetes mellitus with different degrees of obesity: Evidence supporting central obesity
(Editrice Kurtis S R L, 2003)This paper investigates the relative role of the impairment of insulin secretion and action in the pathogenesis of Type 2 diabetes mellitus (T2DM). The parameters indicating insulin secretion and action were calculated ... -
Intraoperative saline-irrigated radiofrequency modified maze procedure for atrial fibrillation
(Elsevier Science Inc, 2002)Background. This study was conducted to evaluate the effectiveness of the saline-irrigated radiofrequency modified Maze operation for treatment of chronic atrial fibrillation and to compare the results of the left and ... -
Intraspinal metalloma resulting in late paraparesis
(Springer, 2005)The metal-related complications caused by orthopedic implants have long been a concern but these problems have been considered mostly in the field of arthroplasty or internal fixation of fractures. The recent prevalence ... -
Intrinsic Dynamics and Causality in Correlated Motions Unraveled in Two Distinct Inactive States of Human beta(2)-Adrenergic Receptor
(Amer Chemical Soc, 2019)The alternative inactive state of the human beta(2)-adrenergic receptor originally exposed in molecular dynamics simulations was investigated using various analysis tools to evaluate causality between correlated residue-pair ... -
Investigation of Allosteric Coupling in Human Beta(2)-Adrenergic Receptor in the Presence of Intracellular Loop 3
(BMC, 2016)Background: This study investigates the allosteric coupling that exists between the intra- and extracellular parts of human beta(2)-adrenergic receptor (beta(2)-AR) in the presence of the intracellular loop 3 (ICL3) which ... -
Investigation of transfusion transmitted viruses in cases clinically suspected of posttransfusion hepatitis with undetermined ethiology
(Pergamon-Elsevier Science Ltd, 2002)Transfusion transmitted viruses (TTV) were investigated in cardiac surgery cases who were previously transfused with blood and/or blood products and were suspected of having posttransfusion hepatitis (PTH) based on the ... -
The involvement of nitric oxide in the analgesic effects of ketamine
(Pergamon-Elsevier Science Ltd, 2002)We investigated the contribution of NO-cyclic GMP (cGMP) pathway to the antinociceptive effects of ketamine in mice by using the nitric oxide synthase inhibitor nitro(g)-L-arginine methyl ester (L-NAME). Intraperitoneal ... -
Is negativity bias intuitive for liberals and conservatives?
(Springer, 2023)Previous research suggests that conservatives (right-wingers) tend to show more negativity bias than liberals (left-wingers) in several tasks. However, the majority of these studies are based on correlational findings and ... -
"It was as if society didn't want a woman to get an abortion": a qualitative study in Istanbul Turkey
(Elsevier Science Inc, 2017)Introduction: In 1983 abortion without restriction as to reason was legalized in Turkey. However at an international conference in 2012 the Prime Minister condemned abortion and announced his intent to draft restrictive ... -
A it-Electron Rich Cage via the Friedel-Crafts Reaction
(Amer Chemical Soc, 2022)A prism-shaped cage was obtained via the Friedel-Crafts reaction in a 2:3 mixture of trisfuryl and bis-isopropenyl precursors, in a remarkable yield of 40% considering six C-C bonds formed in a one-pot manner. The cage ...