Browsing PubMed İndeksli Yayınlar Koleksiyonu by Title
Now showing items 97-116 of 378
-
DNA polymorphism of Pvu II site in the lipoprotein lipase gene in patients with non-insulin dependent diabetes mellitus
(Wiley, 2005)We studied the effect of variation at the lipoprotein lipase (LPL) gene locus on the susceptibility of individuals with non-insulin dependent diabetes mellitus (NIDDM) in a population of 110 NIDDM patients and 91 controls. ... -
Docking studies on monoamine oxidase-B inhibitors: Estimation of inhibition constants (K-i) of a series of experimentally tested compounds
(Pergamon-Elsevier Science Ltd, 2005)Monoamine oxidase (EC1.4.3.4 -
A Docking Study Using Atomistic Conformers Generated via Elastic Network Model for Cyclosporin A/Cyclophilin A Complex
(Taylor & Francis Inc, 2009)Anisotropic network model is used to generate a set of distinct conformations for cylophilin A (CypA). The native structure is deformed to different extents along each of the lowest-frequency modes (first 7 modes) both in ... -
Does normoxemic cardiopulmonary bypass prevent myocardial reoxygenation injury in cyanotic children?
(W.B. Saunders Co Ltd, 2002)Objective: To evaluate whether the deleterious effect of cardiopulmonary bypass (CPB) can be prevented by controlling PaO2 in cyanotic children. Design: Prospective randomized clinical study. Setting: Single university ... -
Does off-pump CAPG reduce gastrointestinal complications?
(Elsevier Science Inc, 2004)Background. The aim of this study was to compare gastrointestinal complications and associated risk factors among patients undergoing cardiac surgery using off- and on-pump revascularization techniques. Methods. A total ... -
Does off-pump coronary artery bypass surgery reduce mortality in high risk patients?
(Forum Multimedia Publishing LLC., 2001)Background: The aim of this retrospective study was to compare outcome in two groups of patients who were classified according to their risk groups and underwent coronary revascularization with or without cardiopulmonary ... -
Drug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening Methodologies
(Frontiers Media Sa, 2016)The diverse cerebral mechanisms implicated in Central Nervous System (CNS) diseases together with the heterogeneous and overlapping nature of phenotypes indicated that multitarget strategies may be appropriate for the ... -
Drug repositioning to propose alternative modulators for glucocorticoid receptor through structure-based virtual screening
(Taylor & Francis Inc, 2022)Drug repositioning has recently become one of the widely used drug design approaches in proposing alternative compounds with potentially fewer side effects. In this study, structure-based pharmacophore modelling and docking ... -
Drug repurposing for coronavirus (COVID-19): in silico screening of known drugs against coronavirus 3CL hydrolase and protease enzymes
(TAYLOR & FRANCIS LTD, 2020)In December 2019, COVID-19 epidemic was described in Wuhan, China, and the infection has spread widely affecting hundreds of thousands. Herein, an effort was made to identify commercially available drugs in order to repurpose ... -
Drying of Polyacrylamide Composite Gels Formed with Various Kappa- Carrageenan Content
(Springer/Plenum Publishers, 2011)Drying of polyacrylamide (PAAm)-kappa-carrageenan (kappa C) composite gels were monitored by using steady-state fluorescence technique. Disc shaped gels were formed from acrylamide (AAm) and N N'- methylenebisacrylamide(Bis) ... -
Early Event Understanding Predicts Later Verb Comprehension and Motion Event Lexicalization
(Amer Psychologıcal Assoc, 2019)Before infants produce words, they can discriminate changes in motion event components such as manner (how an action is performed) and path (trajectory of an action). Individual differences in nonlinguistic event categorization ... -
Early parental causal language input predicts children's later causal verb understanding
(Cambridge Univ Press, 2023)How does parental causal input relate to children's later comprehension of causal verbs? Causal constructions in verbs differ across languages. Turkish has both lexical and morphological causatives. We asked whether (1) ... -
Early Steps in Automated Behavior Mapping via Indoor Sensors
(MDPI, 2017)Behavior mapping (BM) is a spatial data collection technique in which the locational and behavioral information of a user is noted on a plan layout of the studied environment. Among many indoor positioning technologies we ... -
Effect of abdominal obesity on insulin resistance and the components of the metabolic syndrome: Evidence supporting obesity as the central feature
(F D-Communications Inc., 2003)Background: Metabolic syndrome includes abdominal obesity diabetes type 2 hypertension dyslipidemia derangements of fibrinolysis and atherosclerosis. Since abdominal obesity is one of the major components of the insulin ... -
Effect of diclofenac sodium on union of tibial fractures in rats
(2002)Nonsteroidal anti-inflammatory drugs are often used for 7 to 10 days after fracture because of their effects on bone metabolism. This study evaluated the effect of diclofenac sodium, administered at clinical dosage and ... -
Effect of glurenorm on immunohistochemical changes in pancreatic ? cells of rats in experimental diabetes
(2005)Immunohistochemical localization of islets of Langerhans of streptozotocin (65 mg/kg ip) induced diabetic + glurenorm (10 mg/kg po) treated female albino rats revealed increase in number of ? cells and insulin immunoreactivity ... -
Effect of intracellular loop 3 on intrinsic dynamics of human 2-adrenergic receptor
(Bmc, 2013)Background: To understand the effect of the long intracellular loop 3 (ICL3) on the intrinsic dynamics of human beta(2)-adrenergic receptor, molecular dynamics (MD) simulations were performed on two different models, both ... -
Effect of low-dose methyl prednisolone on serum cytokine levels following extracorporeal circulation
(Arnold Hodder Headline Plc., 1999)The systemic inflammatory response to cardiopulmonary bypass (CPB) is associated with increased production of cytokines. This systemic inflammatory response characterized by the activation of interleukin-6 (IL-6) and ... -
Effect of the treatment of brucellosis on leukocyte superoxide dismutase activity and plasma nitric oxide level
(Sage Publications Inc, 2005)Background: The mechanisms by which brucellae evade intracellular killing by polymorphonuclear leukocytes are incompletely understood. In this study we evaluated changes of leukocyte superoxide dismutase (SOD) activity and ... -
The effect of weekend curfews on epidemics: a Monte Carlo simulation
(Tubitak Scientific & Technical Research Council Turkey, 2021)The ongoing COVID-19 pandemic is being responded with various methods, applying vaccines, experimental treatment options, total lockdowns or partial curfews. Weekend curfews are among the methods for reducing the number ...