PubMed İndeksli Yayınlar Koleksiyonu: Recent submissions
Now showing items 161-180 of 378
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Identification of potential inhibitors of human methionine aminopeptidase (type II) for cancer therapy: Structure-based virtual screening, ADMET prediction and molecular dynamics studies
(Elsevier, 2020)Methionine Aminopeptidases MetAPs are divalent-cofactor dependent enzymes that are responsible for the cleavage of the initiator Methionine from the nascent polypeptides. MetAPs are classified into two isoforms: namely, ... -
Identification of Alternative Allosteric Sites in Glycolytic Enzymes for Potential Use as Species-Specific Drug Targets
(Frontiers Media, 2020)Three allosteric glycolytic enzymes, phosphofructokinase, glyceraldehyde-3 phosphate dehydrogenase and pyruvate kinase, associated with bacterial, parasitic and human species, were explored to identify potential allosteric ... -
Design, Synthesis and In Vitro Cytotoxic Activity of New 6,9-Disubstituted Purine Analogues
(Slovensko Kemijsko Drustvo, 2020)A series of new 6,9-disubstituted purine analogs with 4-substituted piperazine at C-6 and 4-substituted benzyl at N-9 were designed and synthesized in four steps. All synthesized compounds (7-26) were screened initially ... -
Metastable reverse-phase droplets within ordered phases: Renormalization-group calculation of field and temperature dependence of limiting size
(AMER PHYSICAL SOC, 2020)Metastable reverse-phase droplets are calculated by renormalization-group theory by evaluating the magnetization of a droplet under magnetic field, matching the boundary condition with the reverse phase and noting whether ... -
Drug repurposing for coronavirus (COVID-19): in silico screening of known drugs against coronavirus 3CL hydrolase and protease enzymes
(TAYLOR & FRANCIS LTD, 2020)In December 2019, COVID-19 epidemic was described in Wuhan, China, and the infection has spread widely affecting hundreds of thousands. Herein, an effort was made to identify commercially available drugs in order to repurpose ... -
Representing the collective past: public event memories and future simulations in Turkey
(Routledge, 2020)Common processes involved in remembering and predicting personal and public events have led researchers to study public events as a part of autobiographical memory. In the present study, we asked for past events and future ... -
Discovery of new azoles with potent activity against Candida spp. and Candida albicans biofilms through virtual screening
(Elsevier, 2020)Systemic candidiasis is a rampant bloodstream infection ofCandidaspp. andC. albicansis the majorpathogen isolated from infected humans. Azoles, the most common class of antifungals which sufferfrom increasing resistance, ... -
Screening of a stentless valve with electron beamed tomograpy 5 years after operation
(2001)[Abstract Not Available] -
A left pulmonary artery aneurysm secondary to pulmonary hypertension
(2001)We report a case of pulmonary trunk aneurysm extending into the left pulmonary artery due to pulmonary hypertension secondary to mitral valve disease. The mitral valve was replaced with a bileaflet mechanical prosthesis. ... -
Effects of intravenous triiodothyronine during coronary artery bypass surgery
(Asia Publishing Exchange Pte Ltd, 2002)A prospective randomized and double-blind study was performed to evaluate whether perioperative triiodothyronine administration has any effect on cardiovascular performance after coronary artery bypass surgery. Sixty ... -
Jejunojejunal intussusception secondary to lipoma in an adult: a case report
(Blackwell Munksgaard, 2002)Lipoma is a rare cause of adult intussusception. We present the CT findings of an adult patient with jejunojejunal intussusception secondary to submucosal lipoma as the lead point in this case report. -
Left versus bi-atrial intraoperative saline-irrigated radiofrequency modified maze procedure for atrial fibrillation
(2003)Background: This study was conducted to evaluate the effectiveness of the saline-irrigated radiofrequency modified maze operation for the treatment of chronic atrial fibrillation (AF) and compare the results of the left ... -
The use of autologous pericardium for complicated mitral valve annulus
(Asia Publishing Exchange Pte Ltd, 2004)The study aims to discuss annular repair using the autologous pericardial patch in cases with severe mitral ring calcification and endocarditis during mitral valve replacement. In the study annular reconstruction was applied ... -
Metabolic syndrome and coronary heart disease [Metabolik Sendrom ve Koroner Kalp Hastalığı]
(2004)[Abstract Not Available] -
Effect of glurenorm on immunohistochemical changes in pancreatic ? cells of rats in experimental diabetes
(2005)Immunohistochemical localization of islets of Langerhans of streptozotocin (65 mg/kg ip) induced diabetic + glurenorm (10 mg/kg po) treated female albino rats revealed increase in number of ? cells and insulin immunoreactivity ... -
Isolated left ventricular diverticulum in an adult: Dynamic contrast-enhanced MRI findings
(2005)[Abstract Not Available] -
The surgical treatment of atrial fibrillation [Atriyal fibrilasyonun cerrahi tedavisi]
(2007)The surgical treatment of atrial fibrillation (AF) has entered a new era with the development of new tools and advanced techniques. The Maze III operation remains as the gold standard for the surgical treatment of AF. ... -
Debate on patentability of biotechnological studies in Turkey.
(2007)The article examines the legislative attempts to regulate the protection of biotechnological inventions through patent in Turkey. In line with the membership process of Turkey to the European Union the Turkish Draft Law ... -
Smoke-free Turkey: Evaluation of outdoor areas of public places
(Academic Press Inc Elsevier Science, 2019)Significance: Secondhand tobacco smoke (SHS) exposure is a major cause of morbidity and mortality around the world. The objective of this study was to evaluate the presence of smoking in outdoor areas of public places in ... -
Self-efficacy and hemodialysis treatment: A qualitative and quantitative approach
(Turkish Association of Nervous and Mental Health, 2013)The theoretically driven approach to the measurement of self-efficacy fails to capture the challenges that hemodialysis patients experience in following their dietary and fluid restrictions. Aims: A combination of qualitative ...