PubMed İndeksli Yayınlar Koleksiyonu: Recent submissions
Now showing items 221-240 of 378
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Evaluation of selective human MAO inhibitory activities of some novel pyrazoline derivatives
(SPRINGER WIEN, 2013)A series of 1-[2-((5-methyl/chloro)-2-benzoxazolinone-3-yl)acetyl]-35-diaryl-45-dihydro-1H-pyrazole derivatives were prepared by reacting 2-((5-methyl/chloro)-2-benzoxazolinone-3-yl)acetylhydrazine with appropriate chalcones. ... -
Insights into the binding mode of new N-substituted pyrazoline derivatives to MAO-A: docking and quantum chemical calculations
(SPRINGER WIEN, 2013)The binding modes of four N-substituted pyrazoline derivatives as novel MAO-A inhibitory agents were investigated using docking and quantum chemical molecular modelling tools. -
Waterpipe tobacco smoke: Characterization of toxicants and exposure biomarkers in a cross-sectional study of waterpipe employees
(Pergamon-Elsevier Science Ltd, 2019)Introduction: Few studies have comprehensively characterized toxic chemicals related to waterpipe use and secondhand waterpipe exposure. This cross-sectional study investigated biomarkers of toxicants associated with ... -
In silico identification of novel and selective monoamine oxidase B inhibitors
(SPRINGER WIEN, 2013)Monoamine oxidases (MAO) A and B are flavin adenine dinucleotides containing enzymes bound to the mitochondrial outer membranes of the cells of the brain liver intestine and placenta as well as platelets. Recently selective ... -
CAMPways: constrained alignment framework for the comparative analysis of a pair of metabolic pathways
(Oxford University Press, 2013)Motivation: Given a pair of metabolic pathways an alignment of the pathways corresponds to a mapping between similar substructures of the pair. Successful alignments may provide useful applications in phylogenetic tree ... -
Acculturation Attitudes and Social Adjustment in British South Asian Children: A Longitudinal Study
(Sage Publications Inc, 2013)A 1-year longitudinal study with three testing points was conducted with 215 British Asian children aged 5 to 11 years to test hypotheses from Berry's acculturation framework. Using age-appropriate measures of acculturation ... -
Analysis of the Patients and Physicians Connection Network on an online Health Information Platform
(IOS Press, 2014)Social network applications have gained popularity in the health domain as they bring health information seekers (patients and alike) and medication advice providers (physicians and other relevant actors) together. By ... -
Examination of Centrality in a Health Social Network
(IOS Press, 2014)Growing importance of health information platforms are acknowledges in recent studies. Such platforms are subject to discussion about an extent to which social network characteristics are realized. The platform under ... -
Cation Effect on Slow Release from Alginate Beads: A Fluorescence Study
(Springer/Plenum Publishers, 2014)In this study spherical alginate beads containing pyranine (P-y) as a fluorescence probe were prepared by ionotropic gelation of a sodium alginate solution. The steady state fluorescence technique was used to study pyranine ... -
BEAMS: backbone extraction and merge strategy for the global many-to-many alignment of multiple PPI networks
(Oxford University Press, 2014)Motivation: Global many-to-many alignment of biological networks has been a central problem in comparative biological network studies. Given a set of biological interaction networks the informal goal is to group together ... -
Group behaviour in physical chemical and biological systems
(Indıan Acad Scıences, 2014)Groups exhibit properties that either are not perceived to exist or perhaps cannot exist at the individual level. Such 'emergent' properties depend on how individuals interact both among themselves and with their surroundings. ... -
Designing of multi-targeted molecules using combination of molecular screening and in silico drug cardiotoxicity prediction approaches
(Elsevier Science Inc, 2014)We have previously investigated and reported a set of phenol- and indole-based derivatives at the binding pockets of carbonic anhydrase isoenzymes using in silico and in vitro analyses. In this study we extended our analysis ... -
Relative group size and minority school success: The role of intergroup friendship and discrimination experiences
(Wiley-Blackwell, 2014)From an intergroup relations perspective relative group size is associated with the quantity and quality of intergroup contact: more positive contact (i.e. intergroup friendship) supports and negative contact (i.e. experienced ... -
Synthesis of some novel hydrazone and 2-pyrazoline derivatives: Monoamine oxidase inhibitory activities and docking studies
(Pergamon-Elsevier Science Ltd, 2014)A novel series of 2-pyrazoline and hydrazone derivatives were synthesized and investigated for their human monoamine oxidase (hMAO) inhibitory activity. All compounds inhibited the hMAO isoforms (MAO-A or MAO-B) competitively ... -
Synthesis molecular modeling in vivo study and anticancer activity of 124-triazole containing hydrazide-hydrazones derived from (S)-naproxen
(Wiley-VCH Verlag GmbH, 2019)A new series of 124-triazole containing hydrazide-hydrazones derived from (S)-naproxen (7a-m) was synthesized in this study. The structures of these compounds were characterized by spectral (Fourier-transform infrared ... -
Discovery of high affinity ligands for beta(2)-adrenergic receptor through pharmacophore-based high-throughput virtual screening and docking
(Elsevier Science Inc, 2014)Novel high affinity compounds for human beta(2)-adrenergic receptor (beta(2)-AR) were searched among the clean drug-like subset of ZINC database consisting of 9928465 molecules that satisfy the Lipinski's rule of five. The ... -
Financial Literacy among Turkish College Students: The Role of Formal Education, Learning Approaches, and Parental Teaching
(Ammons Scientific Ltd, 2014)This study assessed financial literacy and its correlates among Turkish college students with special emphasis on the role of formal education learning approaches and parental influences. Financial literacy was measured ... -
A Computerized Recognition System for the Home-Based Physiotherapy Exercises Using an RGBD Camera
(IEEE, 2014)Computerized recognition of the home based physiotherapy exercises has many benefits and it has attracted considerable interest among the computer vision community. However most methods in the literature view this task as ... -
Growth and shape stability of Cu-Ni core-shell nanoparticles: an atomistic perspective
(Royal Soc Chemistry, 2018)The growth and shape stability of bi-metallic cubic Cu-Ni nanoparticles are studied using atomic-level simulations. Cubic nano-crystals coated with an ultra-thin Cu layer can be readily obtained when Ni cubic nanoparticles ... -
Kinetic models for the dynamical behavior of polyacrylamide (PAAm)-kappa-carrageenan (kappa C) composite gels
(Springer, 2015)A fluorescence method was employed for studying the drying and swelling of PAAm-kappa C composite gels which were formed from acrylamide (AAm) and N N'- methylenebisacrylamide (BIS) with various kappa-carrageenan (kappa ...