Browsing Biyoinformatik ve Genetik Bölümü Koleksiyonu by Issue Date
Now showing items 101-120 of 203
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Aryl butenoic acid derivatives as a new class of histone deacetylase inhibitors: synthesis in vitro evaluation and molecular docking studies
(Scientific Technical Research Council Turkey-Tubitak, 2014)New aryl butenoic acid derivatives have been synthesized by combining hydroxy- or methoxy-substituted phenyl rings as the capping group with a double bond in the short linker as well as metal binding groups enoic ester and ... -
Soman as a wrench in the works of human acetylcholinesterase: Soman induced conformational changes revealed by molecular dynamics simulations
(Amer Chemical Soc, 2014)[Abstract Not Available] -
Kinetic models for the dynamical behavior of polyacrylamide (PAAm)-kappa-carrageenan (kappa C) composite gels
(Springer, 2015)A fluorescence method was employed for studying the drying and swelling of PAAm-kappa C composite gels which were formed from acrylamide (AAm) and N N'- methylenebisacrylamide (BIS) with various kappa-carrageenan (kappa ... -
Flavonoids from Sideritis Species: Human Monoamine Oxidase (hMAO) Inhibitory Activities Molecular Docking Studies and Crystal Structure of Xanthomicrol
(MDPI, 2015)The inhibitory effects of flavonoids on monoamine oxidases (MAOs) have attracted great interest since alterations in monoaminergic transmission are reported to be related to neurodegenerative diseases such as Parkinson's ... -
Fluorescence Study of Film Formation from PS Latex-TiO2 Composites: Effects of TiO2 Content Film Thickness and Particle Size
(Amer Scientific Publishers, 2015)Steady-state fluorescence (SSF) technique in conjunction with UV-visible (UVV) technique atomic force microscope (AFM) and scanning electron microscope (SEM) is used for studying film formation from TiO2 covered polystyrene ... -
Fluorescence study of effect of particle size in PS latex/Al2O3 nanocomposite films
(MANEY PUBLISHING, 2015)Steady state fluorescence and BioUV-Visible techniques were used to study film formation of polystyrene (PS) latex and Al2O3 composites depending on PS particles size and Al2O3 content. Two film series (SmPS/Al2O3 and ... -
How an Inhibitor Bound to Subunit Interface Alters Triosephosphate Isomerase Dynamics
(Cell Press, 2015)The tunnel region at triosephosphate isomerase (TIM)'s dimer interface distant from its catalytic site is a target site for certain benzothiazole derivatives that inhibit TIM's catalytic activity in Trypanosoma cruzi the ... -
Cis-cyclopropylamines as mechanism-based inhibitors of monoamine oxidases
(Wiley-Blackwell, 2015)Cyclopropylamines inhibitors of monoamine oxidases (MAO) and lysine-specific demethylase (LSD1) provide a useful structural scaffold for the design of mechanism-based inhibitors for treatment of depression and cancer. For ... -
Design and synthesis of novel 2-pyrazoline analogues and their hMAO inhibitory activities
(Wiley-Blackwell, 2015)[Abstract Not Available] -
A Wrench in the Works of Human Acetylcholinesterase: Soman Induced Conformational Changes Revealed by Molecular Dynamics Simulations
(Public Library Science, 2015)Irreversible inactivation of human acetylcholinesterase (hAChE) by organophosphorous pesticides (OPs) and chemical weapon agents (CWA) has severe morbidity and mortality consequences. We present data from quantum ... -
Transmembrane helix 6 observed at the interface of beta(2)AR homodimers in blind docking studies
(Taylor & Francis Inc, 2015)Peptide- and protein-protein dockings were carried out on beta(2)-adrenergic receptor (beta(2)AR) to confirm the presence of transmembrane helix 6 (TM6) at the interface region between two beta(2)AR monomers thereby its ... -
Measurement of oxygen diffusion in PS/PNIPAM films using fluorescence quenching
(Taylor & Francis Ltd, 2015)The diffusion of oxygen into pyrene labelled polystyrene (PS) latex/poly(N-isopropylacrylamide) (PNIPAM) composite films (PS/PNIPAM) was studied based on PS content with the use of fluorescence quenching method. Fluorescence ... -
Percolation of glassy regions during photopolymerization of epoxy acrylate in DMF
(Elsevier Science SA, 2015)The gelation of epoxy acrylate (EA) 80% and tripropyleneglycol diacrylate (TPGDA) 20% was studied through the use of photo-differential scanning calorimetric (photo-DSC) technique in the presence of a thioxanthone based ... -
Synthesis and Screening of Human Monoamine Oxidase-A Inhibitor Effect of New 2-Pyrazoline and Hydrazone Derivatives
(Wiley-VCH Verlag GmbH, 2015)A group of 35-diaryl-2-pyrazoline and hydrazone derivatives was prepared via the reaction of various chalcones with hydrazide compounds in ethanol. Twenty original compounds were synthesized. Ten of these original compounds ... -
A comparison of fluorescence and UV-visible spectrometry techniques for thermal phase transitions of agarose gels
(Springer, 2015)In this study thermoreversible phase transitions of high (HMP) and low (LMP) melting point agarose gels were investigated by using the UV-vis and fluorescence spectroscopy techniques. Pyranine was added to the aqueous ... -
The Drosophila fragile X mental retardation protein participates in the piRNA pathway
(Company of Biologists Ltd, 2015)RNA metabolism controls multiple biological processes and a specific class of small RNAs called piRNAs act as genome guardians by silencing the expression of transposons and repetitive sequences in the gonads. Defects in ... -
Microscopic nuclear level densities by the shell model Monte Carlo method
(Cern, 2015)The configuration-interaction shell model approach provides an attractive framework for the calculation of nuclear level densities in the presence of correlations but the large dimensionality of the model space has hindered ... -
Elasticity Study of PAAm-kappa C Composite Prepared in Various kappa C Content and Measured at Several Temperatures
(Polish Acad Sciences Inst Physics, 2015)Polyacrylamide (PAAm)-kappa carrageenan (kappa C) composite gels were prepared via free radical crosslinking copolymerization with various (w/v) percentages of kappa C in the range between 0.5 and 3 (w/v)% of kappa C . ... -
Investigation of allosteric communication pathways in human beta 2-adrenergic receptor
(Wiley-Blackwell, 2015)[Abstract Not Available] -
Universality of elasticity on PAAM-NIPA copolymer gels
(EDP Sciences, 2015)Polyacrylamide (PAAm)-N-isopropylacrylamide (NIPA) copolymers were prepared via free radical crosslinking copolymerization with different molar of NIPA varying in the range between 0 and 2 M. The mechanical properties of ...