Browsing Biyoinformatik ve Genetik Bölümü Koleksiyonu by Title
Now showing items 122-141 of 203
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Measurement of oxygen diffusion in PS/PNIPAM films using fluorescence quenching
(Taylor & Francis Ltd, 2015)The diffusion of oxygen into pyrene labelled polystyrene (PS) latex/poly(N-isopropylacrylamide) (PNIPAM) composite films (PS/PNIPAM) was studied based on PS content with the use of fluorescence quenching method. Fluorescence ... -
Mechanical properties of graphene oxide-polyacrylamide composites before and after swelling in water
(Springer, 2018)Polyacrylamide (PAAm) hydrogels have been proposed for use as promising biomaterials in biomedical and tissue engineering but their poor mechanical and water-retention properties have hindered their development. Graphene ... -
MEDI 333-Histone deacetylase inhibition activity of resveratrol and its analogs
(Amer Chemical Soc, 2007)[Abstract Not Available] -
Microscopic nuclear level densities by the shell model Monte Carlo method
(Cern, 2015)The configuration-interaction shell model approach provides an attractive framework for the calculation of nuclear level densities in the presence of correlations but the large dimensionality of the model space has hindered ... -
Modelling of Swelling by the Fluorescence Technique in Kappa Carrageenan Gels
(Amer Inst Physics, 2011)Kappa (-kappa) carrageenan gels prepared with various carrageenan concentrations in pure water were completely dried and then swelled in water vapor. Steady state fluorescence measurements were performed using a spectrometer ... -
The modifier effects of chymotrypsin and trypsin enzymes on fluorescence lifetime distribution of "N-(1-pyrenyl)maleimide-bovine serum albumin" complex
(Pergamon-Elsevier Science LTD, 2016)Chymotrypsin and trypsin are the well known proteolytic enzymes, both of which are synthesized in the pancreas as their precursors the inactive forms; chymotrypsinogen and trypsinogen and then are released into the duodenum ... -
Molecular docking study based on pharmacophore modeling for novel PhosphodiesteraseIV ınhibitors
(Wiley-VCH Verlag GmbH, 2012)In this study pharmacophore modelling was carried out for novel PhosphodiesteraseIV (PDEIV) inhibitors. A pharmacophore-based virtual screening which resulted in 1959 hit compounds was performed with six chemical databases. ... -
Molecular modifications on carboxylic acid derivatives as potent histone deacetylase inhibitors: Activity and docking studies
(Pergamon-Elsevier Science Ltd, 2009)In the light of known HDAC inhibitors 33 carboxylic acid derivatives were tested to understand the structural requirements for HDAC inhibition activity. Several modifications were applied to develop the structure-activity ... -
Monitoring of dynamical processes in PAAm-MWNTs composites by fluorescence method
(Taylor & Francis Ltd, 2012)Polyacrylamide (PAAm)-multi walled carbon nanotube (MWNT) composites were prepared by free radical cross-linking copolymerization in water. Ammonium persulfate and NN'-methylenebis (acrylamide) (BIS) were used as a free ... -
Monitoring the gelation of polyacrylamide-sodium alginate composite by fluorescence technique
(Taylor & Francis Ltd, 2012)Polyacrylamide (PAAm)-sodium alginate (SA) composite was prepared with different amounts of SA varying in the range between 0.06% and 2% (w/v). The PAAm-SA composite was characterized by the steady-state fluorescence ... -
Multifaceted Dynamics of Janus Oscillator Networks
(Amer Physical Soc., 2019)Recent research has led to the discovery of fundamental new phenomena in network synchronization including chimera states explosive synchronization and asymmetry-induced synchronization. Each of these phenomena has thus ... -
Network dynamics reconstruction from data
(Scıentıfıc Technıcal Research Councıl Turkey-Tubıtak, 2020)We consider the problem of recovering the model of a complex network of interacting dynamical units from time series of observations. We focus on typical networks which exhibit heterogeneous degrees, i.e. where the number ... -
The neural gamma(2)alpha(1)beta(2)alpha(1)beta(2) gamma amino butyric acid ion channel receptor: structural analysis of the effects of the ivermectin molecule and disulfide bridges
(Springer, 2018)While similar to 30% of the human genome encodes membrane proteins only a handful of structures of membrane proteins have been resolved to high resolution. Here we studied the structure of a member of the Cys-loop ligand ... -
New azole derivatives showing antimicrobial effects and their mechanism of antifungal activity by molecular modeling studies
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)Azole antifungals are potent inhibitors of fungal lanosterol 14 alpha demethylase (CYP51) and have been used for eradication of systemic candidiasis clinically. Herein we report the design synthesis and biological evaluation ... -
New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes
(Company of Biologists Ltd, 2017)Cytoplasmic FMRP interacting protein 1 (CYFIP1) is a candidate gene for intellectual disability (ID) autism schizophrenia and epilepsy. It is a member of a family of proteins that is highly conserved during evolution sharing ... -
New pyrazoline bearing 4(3H)-quinazolinone inhibitors of monoamine oxidase: Synthesis biological evaluation and structural determinants of MAO-A and MAO-B selectivity
(Pergamon-Elsevier Science Ltd, 2009)A new series of pyrazoline derivatives were prepared starting from a quinazolinone ring and evaluated for antidepressant anxiogenic and MAO-A and -B inhibitory activities by in vivo and in vitro tests respectively. Most ... -
A NEW THIADIAZINE DERIVATIVE INDUCES OXIDATIVE STRESS DEPENDENT CELL DEATH IN HEPATOCELLULAR CARCINOMA STEM CELLS
(Wiley, 2019)[Abstract Not Available] -
A new thiadiazine derivative induces oxidative stress dependent JNK pathway activation and cell death in hepatocellular carcinoma
(Amer Assoc Cancer Research,, 2019)[Abstract Not Available] -
Novel Mutants of the Aubergine Gene
(Taylor & Francis Inc, 2016)Aubergine is an RNA-binding protein of the Piwi clade functioning in germline in the piRNA pathway that silences transposons and repetitive sequences. Several mutations of this gene exist but they mostly result in truncated ... -
Optical energy band gap of PAAm-GO composites
(Elsevier Science, 2018)Graphene oxide (GO) can be used as an electron acceptor for polymers. The generation of the exciton in such materials is intimately related to the optical band gap. Polyacrylamide (PAAm) - graphene oxide (GO) composites ...