Browsing Biyoinformatik ve Genetik Bölümü Koleksiyonu by Title
Now showing items 185-203 of 203
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Synthesis of some novel hydrazone and 2-pyrazoline derivatives: Monoamine oxidase inhibitory activities and docking studies
(Pergamon-Elsevier Science Ltd, 2014)A novel series of 2-pyrazoline and hydrazone derivatives were synthesized and investigated for their human monoamine oxidase (hMAO) inhibitory activity. All compounds inhibited the hMAO isoforms (MAO-A or MAO-B) competitively ... -
Synthesis, Anticancer Activity on Prostate Cancer Cell Lines and Molecular Modeling Studies of Flurbiprofen-Thioether Derivatives as Potential Target of MetAP (Type II)
(Bentham Science PUBL LTD, 2020)Background: Prostate cancer is still one of the serious causes of mortality and morbidity in men. Despite recent advances in anticancer therapy, there is a still need of novel agents with more efficacy and specificity in ... -
Synthesis, biological evaluation and molecular docking studies of bis-chalcone derivatives as xanthine oxidase inhibitors and anticancer agents
(Elsevier, 2019)In this study, a series of B-ring fluoro substituted bis-chalcone derivatives were synthesized by Claisen-Schmidt condensation reactions and evaluated for their ability to inhibit xanthine oxidase (XO) and growth inhibitory ... -
Synthesis, in silico studies and cytotoxicity evaluation of novel 1,3,4-oxadiazole derivatives designed as potential mPGES-1 inhibitors
(MARMARA UNIV, 2020)A series of new 1,3,4-oxadizole derivatives containing thioether group, has been synthesized to investigate their mPGES-1 inhibitory activities. The synthesized compounds were also evaluated for their anticancer and COX-1/2 ... -
Synthesis, molecular modeling, in vivo study and anticancer activity against prostate cancer of (+) (S)-naproxen derivatives
(Elsevier Masson s.r.l., 2020)In this study, (S)-naproxen thiosemicarbazides (3a-d), 1,2,4-triazoles (4a-c), triazole-thioether hybride compounds (5a-p) were synthesized and their structures (3a, 3d, 4a and 5a-p) were confirmed by FT-IR, 1H NMR,13C ... -
Tailoring The Electrical and Optical Properties of Carbon Nanotube Reinforced Transparent Tio 2 Composites by Varying Nanotube Concentrations
(World Scientific Publ Co Pte Ltd, 2019)In the present work multi-walled carbon nanotube (MWCNT)-doped TiO 2 nanocomposite films were synthesized by sol-gel method. The influence of nanotube concentration on the structural electrical and optical properties of ... -
Temperature Dependence of Oxygen Diffusion into Clay-Doped PS Films
(John Wiley & Sons Inc, 2010)Fluorescence technique was employed for the measurement of the diffusion coefficient of oxygen into polystyrene (PS) latex/modified Na-activated bentonite (MNaLB) clay composite films. Three different MNaLB content (0 5 ... -
Temperature dependence of oxygen diffusion into polymer/carbon nanotube composite films
(Wiley-Blackwell, 2012)This study examines the transport properties of polystyrene (PS)/multiwalled carbon nanotube (MWNT) composite films taking into consideration both MWNT composition and temperature via fluorescence technique. Three different ... -
Temperature Effect on the Elasticity of Acrylamide-n-Isopropylacrylamide Copolymers
(Taylor & Francis Inc, 2018)Acrylamide (AAm) - N-isopropylacrylamide (NIPA) copolymers were prepared via free radical crosslinking copolymerization with various weight percentages (wt%) of AAm and NIPA. The temperature dependence of the compressive ... -
Temperature effect on the swelling of PAAm-kappa-carrageenan composites
(Wiley-Blackwell, 2012)The steady-state fluorescence (SSF) technique was used for studying swelling of disc-shaped polyacrylamide (PAAm)-kappa-carrageenan (kappa C) composites which were prepared by free-radical crosslinking copolymerization at ... -
Thermal Phase Transitions of Agarose in Various Compositions: A Fluorescence Study
(Springer/Plenum Publishers, 2011)The effect of agarose content on thermal phase transitions of the agarose gels was investigated by using Steady State Fluorescence (SSF) method. Scattered light I(sc) and fluorescence intensity I(fl) were monitored against ... -
Thermal Phase Transitions of IOTA Carrageenan in CaCl2 Solutions: A Fluorescence Study
(Taylor & Francis Inc, 2011)The fluorescence technique was employed to study thermal phase transitions of iota (-) carrageenan (IC) in CaCl2 solution. IC gels underwent coil to double helix (c-h) and double helix to dimer (h-d) transitions upon ... -
Thermal rearrangement of 2-acetoxy-266 trimethylbicyclo[3.1.0]hexane: Theoretical elucidation of the mechanism
(Amer Chemical Soc, 2007)[Abstract Not Available] -
Thermal rearrangement of 2-acetoxy-266-trimethylbicyclo[3.1.0]hexane: Theoretical elucidation of the mechanism
(Elsevier Science, 2007)Bicyclohexenes are believed to be the immediate precursors of aromatic compounds. As a part of the exploratory study of thermal aromatization reactions 266-trimethylbicyclo[3.1.0]hexan-2-ol and its ester derivative ... -
Transmembrane helix 6 observed at the interface of beta(2)AR homodimers in blind docking studies
(Taylor & Francis Inc, 2015)Peptide- and protein-protein dockings were carried out on beta(2)-adrenergic receptor (beta(2)AR) to confirm the presence of transmembrane helix 6 (TM6) at the interface region between two beta(2)AR monomers thereby its ... -
Universality in gelation of epoxy acrylate with various photoinitiators: a photo differential scanning calorimetric study
(Taylor & Francis Ltd, 2008)Photo-differential scanning calorimetric (Photo-DSC) technique was used to study the gelation of P-3038 (epoxy acrylate (EA) 75% and tripropyleneglycoldiacrylate (TPGDA) 25%) in the presence of various thioxanthone-based ... -
Universality of elasticity on PAAM-NIPA copolymer gels
(EDP Sciences, 2015)Polyacrylamide (PAAm)-N-isopropylacrylamide (NIPA) copolymers were prepared via free radical crosslinking copolymerization with different molar of NIPA varying in the range between 0 and 2 M. The mechanical properties of ... -
A Wrench in the Works of Human Acetylcholinesterase: Soman Induced Conformational Changes Revealed by Molecular Dynamics Simulations
(Public Library Science, 2015)Irreversible inactivation of human acetylcholinesterase (hAChE) by organophosphorous pesticides (OPs) and chemical weapon agents (CWA) has severe morbidity and mortality consequences. We present data from quantum ... -
The WS(2)dependence on the elasticity and optical band gap energies of swollen PAAm composites
(Sage Publications, 2020)New generation nano-filler polymer composites have many applications including biomedical, electronic and maritime related applications because of their mechanical, electronic and optical properties. The properties of ...
