Browsing Lisansüstü Eğitim Enstitüsü by Author "Akten, Ebru Demet"
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Classification of distinct conformers of beta-2 adrenergic receptor based on binding affinity of ligands through docking studies
Dilcan, Gonca (Kadir Has Üniversitesi, 2017)?2AR is an important drug target and plays a critical role in the relaxation of pulmonary tissues and cardiovascular physiology. We have developed a strategy for classifying various ?2AR conformers as active or inactive ... -
Poz- Adrenerjik Reseptörün Kaba Taneli Moleküler Dinamik Simülasyonu ile farklı Konformasyonlarının Araştırılması
Cakan, Sibel (Kadir Has Üniversitesi, 2012)ß2 adrenergic receptor (ß2AR) is a G protein-coupled receptor, which belongs to thelargest family of membrane proteins and is the target of many drugs. ß2AR is highlyflexible and, able to recognize a wide range of ligands ...