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In silico design of selective neuronal nitric oxide synthase inhibitors in order to prevent neurodegenerative diseases
(Kadir Has Üniversitesi, 2013)
Nitric Oxide syntheses (NOS) are the family of enzymes which catalyzes the oxidation L-Arginine amino acid to nitric oxide molecule (NO) L-citrulline. Mammals contain three different NOS isozymes: Neuronal NOS (nNOS, in ...