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In silico design of selective monoamine Oxidase B inhibitors using indane ring
(Kadir Has Üniversitesi, 2013)
in the present work 209952 analogs of an indane scaffold were created using various fragment moieties at different position of indane ring. CHEMPLP module of GOLD program is utilized in the screening process. in order to ...
In silico design of novel and highly selective cyclooxygenase-2 inhibitors
(Kadir Has Üniversitesi, 2014)
For many years, prevention of inflammation is achieved by inhibition of both cyclooxygenase (COX) enzymes; the eventual outcome is gastrointestinal toxicity. Selective inhibitor design for COX-2 initialized just after ...