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Structure Prediction of TB RPOB and its Mutations Binding Analysis
(Kadir Has Üniversitesi, 2012)
--Today Tuberculosis is a disease that is still a high-risk categories. Rifampicin is a drug that.s used common in the treatment of TB. We know that the effect of this drug in the region of RNA polymerase on TB. Unfortunately ...
Molacilar Dynamics Studies oh human dat and its natural ligand dopamine
(Kadir Has Üniversitesi, 2012)
The dopamine transporter (DAT) which is a member of Neurotransmitter sodium symporters (NSSs) family takes place in dopaminergic neurotransmission. Therefore it is a major molecular target for numerous drugs including the ...
In Silico Inhibitor Design For Monomine Oxidase A And B Isozymes
(Kadir Has Üniversitesi, 2012)
in this thesis study MAO-A and MAO-B isozymes are selected as target enzymes that have important role of regulation of diseases such as ..Parkinson Alzheimer and depression... MAO isozymes which catalyze the oxidation of ...