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Synthesis Molecular Docking and Anticancer Activity of Diflunisal Derivatives as Cyclooxygenase Enzyme Inhibitors
(MDPI, 2018)
Cyclooxygenase enzymes play a vital role in inflammatory pathways in the human body. Apart from their relation with inflammation the additional involvement of COX-2 enzyme with cancer activity was recently discovered. In ...
Fractal Features and Structural Morphological Optical Characteristics of Sol-Gel Derived Silica Nanoparticled Thin Films
(Polish Acad Sciences Inst Physics, 2018)
Nanostructured silica films using a simple and effective sol-gel spin coating technique were synthesized and the influence of ammonia/sol ratios on the particle size and thickness of this film was investigated. In addition ...
"2-pirazolin yapısındaki yeni bir bileşiğin sentezi, moleküler modellemesi ve monoaminoksidaz inhibitörü etkisinin araştırılması"
(Türkiye Halk Sağlığı Kurumu, 2018)
Amaç: Nöromediatörlerin yıkımından sorumlu olan
monoamin oksidaz (MAO) enziminin izoformlarının
(MAO-A ve -B) birçok hastalık ile yakından ilişkili olduğu;
MAO inhibitörlerinin depresyon, Parkinson ve Alzheimer
hastalığı ...