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Design of novel and potent inhibitors for mPGES-1 enzyme via in silico screening
(Kadir Has Üniversitesi, 2021)
To prevent inflammation in the body, non-steroidal anti-inflammatory drugs act by suppressing PGE2 production as a result of non-selective inhibition of both COX-1 and COX-2 enzymes. As a result of the inhibition of COX-1 ...