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Protective effects of a calcium channel blocker on apoptosis in thymus of neonatal STZ-diabetic rats
(Elsevier GMBH Urban & Fischer Verlag, 2005)
Streptozotocin (STZ) is known to induce insulin-dependent diabetes in experimental animals. In STZ-induced diabetes atrophy of the thymus is caused by elevated intracellular calcium levels leading to apoptosis. Hyperglycemia ...