Browsing PubMed İndeksli Yayınlar Koleksiyonu by Title
Now showing items 240-259 of 378
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National identity predicts public health support during a global pandemic
(Nature Portfolio, 2022)Understanding collective behaviour is an important aspect of managing the pandemic response. Here the authors show in a large global study that participants that reported identifying more strongly with their nation reported ... -
Nematic ordering in the Heisenberg spin-glass system in three dimensions
(Amer Physical Soc, 2023)Nematic ordering, where the spins globally align along a spontaneously chosen axis irrespective of direction, occurs in spin-glass systems of classical Heisenberg spins in d = 3. In this system where the nearest-neighbor ... -
Network structural origin of instabilities in large complex systems
(Amer Assoc Advancement Science, 2022)A central issue in the study of large complex network systems, such as power grids, financial networks, and ecological systems, is to understand their response to dynamical perturbations. Recent studies recognize that many ... -
The neural gamma(2)alpha(1)beta(2)alpha(1)beta(2) gamma amino butyric acid ion channel receptor: structural analysis of the effects of the ivermectin molecule and disulfide bridges
(Springer, 2018)While similar to 30% of the human genome encodes membrane proteins only a handful of structures of membrane proteins have been resolved to high resolution. Here we studied the structure of a member of the Cys-loop ligand ... -
New 2-Pyrazoline and Hydrazone Derivatives as Potent and Selective Monoamine Oxidase A Inhibitors
(AMER CHEMICAL SOC, 2021-02)Thirty compounds having 1-[2-(5-substituted-2-benzoxazolinone-3-yl) acetyl]-3,5-disubstitutedphenyl-2-pyrazoline structure and nine compounds having N'-(1,3-disubstitutedphenylallylidene)-2-(5-substituted- 2-benzoxazolin ... -
New azole derivatives showing antimicrobial effects and their mechanism of antifungal activity by molecular modeling studies
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2017)Azole antifungals are potent inhibitors of fungal lanosterol 14 alpha demethylase (CYP51) and have been used for eradication of systemic candidiasis clinically. Herein we report the design synthesis and biological evaluation ... -
New Biological and Chemical Evidences of Two Lamiaceae Species (Thymbra capitata and Thymus sipyleus subsp. rosulans): In Vitro, In Silico and Ex Vivo Approaches
(Mdpi, 2022)In this study, the methanolic and infusion extracts of two species, Thymbra capitata and Thymus sipyleus subsp. rosulans, were tested for their chemical composition and biological abilities (antioxidant, enzyme inhibitory ... -
New Human Monoamine Oxidase A Inhibitors with Potential Anti- Depressant Activity: Design, Synthesis, Biological Screening and Evaluation of Pharmacological Activity
(Bentham Science, 2017)Aim and objective: Depression is a momentous disease that can greatly reduce the quality of life and cause death. In depression, neurotransmitter levels such as serotonine, dopamine and noradrenaline are impaired. Monoamine ... -
New insights from children with early focal brain injury: Lessons to be learned from examining STEM-related skills
(Wiley, 2019)The study of cognitive development in children with early brain injury reveals crucial information about the developing brain and its plasticity. However information on long-term outcomes of these children especially in ... -
New insights into the regulatory function of CYFIP1 in the context of WAVE- and FMRP-containing complexes
(Company of Biologists Ltd, 2017)Cytoplasmic FMRP interacting protein 1 (CYFIP1) is a candidate gene for intellectual disability (ID) autism schizophrenia and epilepsy. It is a member of a family of proteins that is highly conserved during evolution sharing ... -
A new lung cancer detection method based on the chest CT images using Federated Learning and blockchain systems
(Elsevier, 2023)With an estimated five million fatal cases each year, lung cancer is one of the significant causes of death worldwide. Lung diseases can be diagnosed with a Computed Tomography (CT) scan. The scarcity and trustworthiness ... -
New modification in otoplasty: Anterior approach
(Lippincott Williams & Wilkins, 2001)After harvesting the conchal cartilage in a large series of secondary rhinoplasties using the anterior approach there was a marked improvement in the shape of the auricle with unnoticeable scarring hidden under the convolution ... -
New pyrazoline bearing 4(3H)-quinazolinone inhibitors of monoamine oxidase: Synthesis biological evaluation and structural determinants of MAO-A and MAO-B selectivity
(Pergamon-Elsevier Science Ltd, 2009)A new series of pyrazoline derivatives were prepared starting from a quinazolinone ring and evaluated for antidepressant anxiogenic and MAO-A and -B inhibitory activities by in vivo and in vitro tests respectively. Most ... -
A new technique for abdominal heart transplantation in rats
(Edizioni Minerva Medica, 2003)Experimental studies in animals play a major role in the progress of medicine. Different surgical techniques have been described for heterotopic heart transplantation in rats. in this study we introduce a new technique for ... -
A new triazolothiadiazine derivative inhibits stemness and induces cell death in HCC by oxidative stress dependent JNK pathway activation
(Nature Portfolio, 2022)Hepatocellular carcinoma (HCC) is a highly heterogeneous cancer, and resistant to both conventional and targeted chemotherapy. Recently, nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to decrease the incidence ... -
Novel 1,2,4-triazoles derived from Ibuprofen: synthesis and in vitro evaluation of their mPGES-1 inhibitory and antiproliferative activity
(Springer, 2022)Some novel triazole-bearing ketone and oxime derivatives were synthesized from Ibuprofen. In vitro cytotoxic activities of all synthesized molecules against five cancer lines (human breast cancer MCF-7, human lung cancer ... -
Novel Application Software for the Semi-Automated Analysis of Infrared Meibography Images
(2019)Purpose: To develop semi-automated application software that quickly analyzes infrared meibography images taken with the CSO Sirius Topographer (CSO, Italy) and to compare them to the manual analysis system on the device ... -
Novel Mutants of the Aubergine Gene
(Taylor & Francis Inc, 2016)Aubergine is an RNA-binding protein of the Piwi clade functioning in germline in the piRNA pathway that silences transposons and repetitive sequences. Several mutations of this gene exist but they mostly result in truncated ... -
Off-pump coronary artery bypass grafting with use of the octopus 2 stabilization system
(2000)Background: The treatment of coronary artery disease has evolved rapidly over the last two decades. The gold standard of surgical revascularization, the on-pump coronary artery bypass graft, has been challenged by the ...
