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Citation - WoS: 4
Citation - Scopus: 6
Abortion Services at Hospitals in Istanbul
(Taylor & Francis Ltd, 2017) O'Neil, Mary Lou
Objective: Despite the existence of a liberal law on abortion in Turkey there is growing evidence that actually securing an abortion in Istanbul may prove difficult. This study aimed to determine whether or not state hospitals and private hospitals that accept state health insurance in Istanbul are providing abortion services and for what indications. Method: Between October and December 2015 a mystery patient telephone survey of 154 hospitals 43 public and 111 private in Istanbul was conducted. Results: 14% of the state hospitals in Istanbul perform abortions without restriction as to reason provided in the current law while 60% provide the service if there is a medical necessity. A quarter of state hospitals in Istanbul do not provide abortion services at all. 48.6% of private hospitals that accept the state health insurance also provide for abortion without restriction while 10% do not provide abortion services under any circumstances. Key conclusions: State and private hospitals in Istanbul are not providing abortion services to the full extent allowed under the law. The low numbers of state hospitals offering abortions without restriction indicates a de facto privatization of the service. This same trend is also visible in many private hospitals partnering with the state that do not provide abortion care. While many women may choose a private provider the lack of provision of abortion care at state hospitals and those private hospitals working with the state leaves women little option but to purchase these services from private providers at some times subtantial costs.
Citation - WoS: 22
Citation - Scopus: 25
Absolute Configuration and Biological Profile of Pyrazoline Enantiomers as Mao Inhibitory Activity
(Wiley, 2019) Goksen, Umut Salgin; Sarıgül, Sevgi; Bultinck, Patrick; Herrebout, Wouter; Doğan, İlknur; Yelekçi, Kemal; Uçar, Gülberk; Kelekçi, Nesrin Gökhan
A new racemic pyrazoline derivative was synthesized and resolved to its enantiomers using analytic and semipreparative high-pressure liquid chromatography. The absolute configuration of both fractions was established using vibrational circular dichroism. The in vitro monoamine oxidase (MAO) inhibitory profiles were evaluated for the racemate and both enantiomers separately for the two isoforms of the enzyme. The racemic compound and both enantiomers were found to inhibit hMAO-A selectively and competitively. In particular the R enantiomer was detected as an exceptionally potent and a selective MAO-A inhibitor (K-i = 0.85 x 10(-3) +/- 0.05 x 10(-3) mu M and SI: 2.35 x 10(-5)) whereas S was determined as poorer compound than R in terms of K-i and SI (0.184 +/- 0.007 and 0.001). The selectivity of the enantiomers was explained by molecular modeling docking studies based on the PDB enzymatic models of MAO isoforms.
Citation - Scopus: 2
Accented Essays: Documentary as Artistic Practice in Contemporary Audiovisual Works From Turkey
(Routledge Journals, Taylor & Francıs Ltd, 2019) Akçalı Kuyucu, Elif
This article looks at the use of documentary filmmaking in contemporary artistic practices in Turkey, specifically focusing on three works that adopt a first-person, subjective viewpoint: Didem Pekun's Of Dice and Men (2016), Sener ozmen's How to Tell of Peace to a Living Dove? (2015), and Aykan Safoglu's Off-White Tulips (2013). Made by artists in transition, these films tackle themes of belonging and identity through stylistic choices proper to essayistic filmmaking, which allow these works to be regarded as accented essays. The personal questions raised through the aesthetics they employ become relevant to collective issues of culture, history, and memory, offering an alternative understanding of the social context, which was largely affected by the political events during the period in which they were made.
Citation - WoS: 32
Citation - Scopus: 35
Activating Reflective Thinking With Decision Justification and Debiasing Training
(Society for Judgment and Decision making, 2020) İsler, Ozan; Yılmaz, Onurcan; Doğruyol, Burak
Manipulations for activating reflective thinking, although regularly used in the literature, have not previously been systematically compared. There are growing concerns about the effectiveness of these methods as well as increasing demand for them. Here, we study five promising reflection manipulations using an objective performance measure — the Cognitive Reflection Test 2 (CRT-2). In our large-scale preregistered online experiment (N = 1,748), we compared a passive and an active control condition with time delay, memory recall, decision justification, debiasing training, and combination of debiasing training and decision justification. We found no evidence that online versions of the two regularly used reflection conditions — time delay and memory recall — improve cognitive performance. Instead, our study isolated two less familiar methods that can effectively and rapidly activate reflective thinking: (1) a brief debiasing training, designed to avoid common cognitive biases and increase reflection, and (2) simply asking participants to justify their decisions.
Citation - Scopus: 5
The Akp Story: Turkey's Bumpy Reform Path Towards the European Union
(2011) McDonald, Deniz Bingöl
The Justice and Development Party (AKP) government between 2002 and 2007 managed to accomplish unprecedented economic reforms maintaining 8% growth and passed legislation to change Turkey into a more democratic country in line with the Copenhagen political conditions. After being rewarded with the start of accession negotiations in 2005 and an electoral landslide in 2007 AKP's second term in office is in stark contrast with its earlier days of glory. AKP disengaged itself from the IMF agreement and took EU reforms off the top of its agenda bringing half a decade of political and economic reforms to a halt. The paper argues that AKP utilized the credibility of IMF and EU support to defeat its domestic rivals but once the external incentives lessened AKP turned inwards to consolidate its power and cared for little else. The first part of the paper explores how AKP managed to construct such a broad reform consensus and assesses the role of the external influence. The second part explores why and how this reform consensus fell apart.
Citation - WoS: 1
Citation - Scopus: 1
Analysis of the Patients and Physicians Connection Network on an Online Health Information Platform
(IOS Press, 2014) Aydın, Mehmet Nafiz; Perdahci, N. Ziya
Social network applications have gained popularity in the health domain as they bring health information seekers (patients and alike) and medication advice providers (physicians and other relevant actors) together. By employing a network science perspective this research is aimed to understand an information network establishing connections among and between information seekers and providers. We found that such a connection network surfaces most of the essential characteristics of a typical complex network. Furthermore a detailed structural analysis shows some intriguing relations and connection behaviours in the network. Implications of the findings are discussed from the perspectives of medical informatics and social network analysis.
Citation - WoS: 8
Citation - Scopus: 9
Antifungal Screening and in Silico Mechanistic Studies of an In-House Azole Library
(2019) Sarı, Suat; Kart, Didem; Sabuncuoğlu, Suna; Doğan, İnci Selin; Özdemir, Zeynep; Bozbey, İrem; Gencel, Melis; Eşsiz, Şebnem; Reynisson, Jóhannes; Karakurt, Arzu; Saraç, Selma; Dalkara, Sevim
Systemic Candida infections pose a serious public health problem with high morbidity and mortality. C. albicans is the major pathogen identified in candidiasis; however, non-albicans Candida spp. with antifungal resistance are now more prevalent. Azoles are first-choice antifungal drugs for candidiasis; however, they are ineffective for certain infections caused by the resistant strains. Azoles block ergosterol synthesis by inhibiting fungal CYP51, which leads to disruption of fungal membrane permeability. In this study, we screened for antifungal activity of an in-house azole library of 65 compounds to identify hit matter followed by a molecular modeling study for their CYP51 inhibition mechanism. Antifungal susceptibility tests against standard Candida spp. including C. albicans revealed derivatives 12 and 13 as highly active. Furthermore, they showed potent antibiofilm activity as well as neglectable cytotoxicity in a mouse fibroblast assay. According to molecular docking studies, 12 and 13 have the necessary binding characteristics for effective inhibition of CYP51. Finally, molecular dynamics simulations of the C. albicans CYP51 (CACYP51) homology model's catalytic site complexed with 13 were stable demonstrating excellent binding.
Citation - WoS: 11
Citation - Scopus: 11
Application of Epidemic Models To Phase Transitions
(Taylor & Francis Ltd, 2012) Bilge, Ayşe Hümeyra; Pekcan, Önder; Gürol, M. V.
The Susceptible-Infected-Recovered (SIR) and Susceptible-Exposed-Infected-Recovered (SEIR) models describe the spread of epidemics in a society. In the typical case, the ratio of the susceptible individuals fall from a value S-0 close to 1 to a final value S-f, while the ratio of recovered individuals rise from 0 to R-f = 1 - S-f. The sharp passage from the level zero to the level R-f allows also the modeling of phase transitions by the number of "recovered" individuals R(t) of the SIR or SEIR model. In this article, we model the sol-gel transition for polyacrylamide-sodium alginate (SA) composite with different concentrations of SA as SIR and SEIR dynamical systems by solving the corresponding differential equations numerically and we show that the phase transitions of "classical" and "percolation" types are represented, respectively, by the SEIR and SIR models.
Citation - WoS: 2
Citation - Scopus: 3
Aryl Butenoic Acid Derivatives as a New Class of Histone Deacetylase Inhibitors: Synthesis in Vitro Evaluation and Molecular Docking Studies
(Scientific Technical Research Council Turkey-Tubitak, 2014) Esiyok, Peruze Ayhan; Seven, özlem; Eymur, Guluzar; Tatar, Gamze Bora; Erden, Didem Dayangaç; Yelekçi, Kemal; Yurter, Hayat; Demir, Ayhan S.
New aryl butenoic acid derivatives have been synthesized by combining hydroxy- or methoxy-substituted phenyl rings as the capping group with a double bond in the short linker as well as metal binding groups enoic ester and salts bearing either methyl or morpholine. These compounds have been shown to possess promising histone deacetylase inhibition activities via in vitro fluorometric assay and molecular docking studies.
Citation - WoS: 4
Citation - Scopus: 7
Atomic Force Microscopy and Spectroscopy Studies of Annealed Ce/Ti Mixed Oxide Thin Films Prepared by Sol-Gel Process
(Elsevier Science Bv, 2006) Ghodsi, Farhad E.; Tepehan, Fatma Zehra; Tepehan, Galip Gültekin
Mixed Ce/Ti/Zr oxide thin films with a molar ratio of 0.5:0.25:0.25 were prepared using the sol-gel process and deposited on glass substrates by the dip coating technique. The effect of heat treatment temperature on surface morphology of the films was examined by atomic force microscopy AFM. The optical transmittance and reflectance of the films were measured over the spectral range from 350 to 1000 nm. The refractive index and extinction coefficient and thickness of the films were determined as a function of the heat treatment temperature. The refractive index increased from 1.51 to 2.02 at lambda = 600 nm and the extinction coefficient values increased from 0.006 to 0.094 while the thickness of the films decreased from 81 nm to 45 nm when annealing temperature increased from 100 degrees C to 500 degrees C. The results show that the optical properties and surface morphology of the mixed Cc/Ti/Zr oxide thin films were affected by annealing temperature. (c) 2006 Elsevier B.V. All rights reserved.
Citation - WoS: 1
Citation - Scopus: 2
A Bayesian Approach To Developing a Strategic Early Warning System for the French Milk Market
(Halmstad University, 2017) Bisson, Christophe; Gürpınar, Furkan
A new approach is provided in our paper for creating a strategic early warning system allowing the estimation of the future state of the milk market as scenarios. This is in line with the recent call from the EU commission for tools that help to better address such a highly volatile market. We applied different multivariate time series regression and Bayesian networks on a pre-determined map of relations between macro-economic indicators. The evaluation of our findings with root mean square error (RMSE) performance score enhances the robustness of the prediction model constructed. Our model could be used by competitive intelligence teams to obtain sharper scenarios, leading companies and public organisations to better anticipate market changes and make more robust decisions.
Citation - WoS: 3
Citation - Scopus: 3
Beliefs of Living Donors About Recipients' End-Stage Liver Failure and Surgery for Organ Donation
(Elsevier Science Inc, 2017) Krespi-Boothby, Margörit Rita; Tankurt, A.; Acarli, Koray; Kanmaz, Turan; Yankol, Yucel; Kalayoğlu, Murat
Background. The concept of beliefs could provide a basis for how donors may perceive recipients' end-stage liver failure (ESLF) and surgery for organ donation. However there is no such quantitative study. Therefore the objective of this study was to explore beliefs of living donors about recipients' ESLF and surgery for organ donation. Methods. The sample comprised 16 living donors who donated a part of their liver to a patient who had ESLF. The data were analyzed by following established procedures for inductive qualitative analysis. Results. Analysis showed that donors' beliefs can be viewed in a number of groups. Beliefs about recipients' ESLF included diverse explanations for ESLF (blaming oneself and physicians) and physical symptoms (developmental slowing down). Beliefs about being a donor included reasons for being a donor (performing a good deed being healed) barriers to being a donor (other people being ignorant and selfish) ways to manage these barriers (following one's gut feeling) and factors facilitating being a donor (the feeling that one does not have many people to leave behind). Beliefs about surgery for organ donation included physical effects (pain feeling stiff). Beliefs about organ donation included views that general organ donation should be encouraged and that people's awareness should be raised. Conclusions. Existing psychological perspectives could help to interpret some beliefs. Nevertheless other beliefs not previously reported could be considered as targets for individual consultations/psycho-educational programs for fostering emotional well-being.
Citation - WoS: 8
Citation - Scopus: 9
Between Anchors and Aspirations: a New Family of Bargaining Solutions
(Springer, 2019) Karagözoğlu, Emin; Keskin, Kerim; Özcan-Tok, Elif
We study the salience and power of reference points in determining the effective anchors and aspirations in bargaining problems. Along this line we enrich the analysis of the standard bargaining model with two new parameters: the first parameter can be interpreted as the effectiveness (or salience) of the reference point in determining the anchor whereas the second parameter can be interpreted as its effectiveness in shaping agents' aspirations. Utilizing these parameters we provide a unifying framework for the study of bargaining problems with a reference point. The two-parameter family of bargaining solutions we obtain encompasses some well-known solutions as special cases. We offer multiple characterizations for each individual member of this family as well as two characterizations for the whole solution family in bilateral bargaining problems.
Citation - WoS: 5
Citation - Scopus: 7
Biclustering Expression Data Based on Expanding Localized Substructures
(Springer-Verlag Berlin, 2009) Erten, Cesim; Sözdinler, Melih
Biclustering gene expression data is the problem of extracting submatrices of genes and conditions exhibiting significant correlation across both the rows and the columns of a data matrix of expression values. We provide a method LEB (Localize-and-Extract Biclusters) which reduces the search space into local neighborhoods within the matrix by first localizing correlated structures. The localization procedure takes its roots from effective use of graph-theoretical methods applied to problems exhibiting a similar structure to that of biclustering. Once interesting structures are localized the search space reduces to small neighborhoods and the biclusters are extracted from these localities. We evaluate the effectiveness of our method with extensive experiments both using artificial and real datasets.
Citation - WoS: 4
Citation - Scopus: 7
Border as "zone of Indistinction": the State of Exception and the Spectacle of Terror Along Turkey's Border With Syria
(Sage Publications Inc, 2018) Tuncer-Gürkaş, Ezgi
Turkey's border with Syria today is a laboratory in which biopolitics and the spectacle coincide in new ways. As a consequence of the ongoing war between the state and Kurdish insurgents, and the state of emergency accompanying it, this border region has incrementally transformed into a zone of indistinction in which the spatial concepts of inside and outside interpenetrate. As exception is normalized, the logic of the camp (in Agamben's sense) tends to become a dispositif. Exceptional routines are being exercised in this border region both to (re)construct the figure of the Kurd as a citizen and to generalize the domain of the camp, while also producing bare life in the context of counterterrorism. However, the Kurd as a subject cannot be ambiguously constructed, neither can the region be politically homogenized. Based on multisited fieldwork in the border city of Mardin, I claim that this zone of indistinction is simultaneously the place of revolt and resistance for the Kurdish case. Against this backdrop, the article argues the practical implications of counterterrorism policies in the region by focusing on how the state of exception is enforced on the Kurdish population as a biopolitical tool while being represented as a public spectacle to the rest of Turkey.
Citation - WoS: 2
Citation - Scopus: 6
Branch Outage Simulation Based Contingency Screening by Gravitational Search Algorithm
(Praise Worthy Prize Srl, 2012) Ceylan, Oğuzhan; Özdemir, Aydoğan; Dağ, Hasan
Power systems contingency analysis is an important issue for electric power system operators. This paper performs branch outage simulation based contingency screening using a bounded network approach. Local constrained optimization problem representing the branch outage phenomena is solved by the gravitational search algorithm. The proposed method is applied to IEEE 14 30 57 and 118 Bus Test systems and its performance from the point of capturing violations is evaluated. In addition false alarms and the computational accuracy of the proposed method are also analyzed by using scattering diagrams. Finally the proposed gravitational search based contingency screening is compared with full AC load flow solutions from the point of computational speed. Copyright (C) 2012 Praise Worthy Prize S.r.l. - All rights reserved.
Citation - WoS: 2
Citation - Scopus: 5
Breaking the Rules in Interactive Media Design Education
(Routledge Journals Taylor & Francis Ltd, 2009) Özcan, Oğuzhan; Yantaç, Asım Evren; O'Neil, Mary Lou
In today's interactive media design it is difficult for a designer to create aesthetic innovations and to break free from ordinariness. The most important factor limiting interactive media design aesthetics is that education seems to be more focused on following traditional rules of interaction design rather than innovative approaches. These rules limit creativity and often relegate design students to producing ordinary interface solutions. This is especially burdensome for us as teachers. In order to address this problem we developed an education model inspired by Lars von Trier's film Five Obstructions. We call this model 'breaking the rules'. In the 'breaking the rules' approach students produce within a range of probabilities design problem solutions in cases of total or partial visual/auditory/tactile obstructions. The most important outputs of the model are (1) to make design student think/look outside of the ordinary (2) to produce unusual solutions (3) to maximise design solutions with sound.
Citation - WoS: 2
Citation - Scopus: 2
Broadband Matching Via Reflection Function Optimization
(Wiley, 2017) Şengül, Metin Y.
In this paper a practical approach is presented for designing broadband matching networks via reflection function optimization. In the proposed algorithm the input or output reflection function of the matching network is expressed in terms of three real polynomials describing the matching network load and generator reflection coefficients. Next one of the polynomials is optimized to get minimum reflection function values in the passband. Then matching network topology and element values are obtained via the formed input reflection coefficient expression. Two examples are presented to explain the usage of the new approach. Copyright (c) 2016 John Wiley & Sons Ltd.
Citation - WoS: 2
Citation - Scopus: 3
Broadband Matching Via Unequal Length Cascaded Transmission Lines
(World Scientific Publ Co Pte Ltd, 2017) Şengül, Metin Y.
In this paper a new approach based on the real frequency technique (RFT) has been proposed to solve broadband matching problems using cascaded unequal length transmission lines. At the end of the design process optimum characteristic impedance and delay values of transmission lines are obtained. Two examples are given to illustrate the utilization of the proposed approach.
Broadband Microwave Amplifier Design With Lumped Elements
(Walter De Gruyter Gmbh, 2016) Şengül, Metin Y.
This study introduces a broadband microwave amplifier design that utilizes the measured scattering parameters of active devices without assuming an initial topology for the matching networks or an analytic form of the system transfer function. The algorithm can be extended to design multistage broadband microwave amplifiers. An example is given to illustrate the application of the proposed method. It was found that the proposed method provides very good initials for CAD tools to further improve amplifier performance by working on the element values.

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