Hydrogels From Protein-Polymer Conjugates: a Pathway To Next-Generation Biomaterials

dc.authoridPoyraz, Yagmur/0000-0002-5318-7978
dc.authorscopusid59386008400
dc.authorscopusid59385393300
dc.authorscopusid58986629200
dc.authorscopusid57736023600
dc.authorscopusid59660454800
dc.authorscopusid59661154200
dc.authorscopusid6507297154
dc.authorwosidAkten, Ebru/Aag-7752-2019
dc.authorwosidUysal, Bengü/G-9131-2019
dc.authorwosidPoyraz, Yağmur/Mik-5504-2025
dc.contributor.authorAlayoubi, Oubadah
dc.contributor.authorPoyraz, Yagmur
dc.contributor.authorHassan, Gana
dc.contributor.authorGul, Sumeyye Berfin
dc.contributor.authorCalhan, Nergiz
dc.contributor.authorMert Sahin, Naz Mina
dc.contributor.authorPekcan, Onder
dc.date.accessioned2025-03-15T20:07:03Z
dc.date.available2025-03-15T20:07:03Z
dc.date.issued2025
dc.departmentKadir Has Universityen_US
dc.department-temp[Alayoubi, Oubadah; Hassan, Gana; Gul, Sumeyye Berfin; Calhan, Nergiz; Kutlu, Aylin] Kadir Has Univ, Sch Grad Studies, Mat Sci & Nanotechnol, TR-34083 Istanbul, Turkiye; [Poyraz, Yagmur; Mert Sahin, Naz Mina; Gautam, Megha] Kadir Has Univ, Sch Grad Studies, Computat Sci & Engn, TR-34083 Istanbul, Turkiye; [Uysal, Bengu Ozugur] Altinbas Univ, Fac Engn & Architecture, Dept Basic Sci, TR-34218 Istanbul, Turkiye; [Akten, Ebru Demet; Pekcan, Onder] Kadir Has Univ, Fac Engn & Nat Sci, TR-34083 Istanbul, Turkiyeen_US
dc.descriptionPoyraz, Yagmur/0000-0002-5318-7978en_US
dc.description.abstractHybrid hydrogels from protein-polymer conjugates are biomaterials formed via the chemical bonding of a protein molecule with a polymer molecule. Protein-polymer conjugates offer a variety of biological properties by combining the mechanical strength of polymers and the bioactive functionality of proteins. These properties allow these conjugates to be used as biocompatible components in biomedical applications. Protein-polymer conjugation is a vital bioengineering strategy in many fields, such as drug delivery, tissue engineering, and cancer therapy. Protein-polymer conjugations aim to create materials with new and unique properties by combining the properties of different molecular components. There are various ways of creating protein-polymer conjugates. PEGylation is one of the most common conjugation techniques where a protein is conjugated with Polyethylene Glycol. However, some limitations of PEGylation (like polydispersity and low biodegradability) have prompted researchers to devise novel synthesis techniques like PEGylation, where synthetic polypeptides are used as the polymer component. This review will illustrate the properties of protein-polymer conjugates, their synthesis methods, and their various biomedical applications.en_US
dc.description.sponsorshipPersonal Research Funds of Onder Pekcanen_US
dc.description.sponsorshipPersonal Research Funds of Onder Pekcan funded this research at Kadir Has University.en_US
dc.description.woscitationindexScience Citation Index Expanded
dc.identifier.doi10.3390/gels11020096
dc.identifier.issn2310-2861
dc.identifier.issue2en_US
dc.identifier.pmid39996639
dc.identifier.scopus2-s2.0-85219170336
dc.identifier.scopusqualityQ3
dc.identifier.urihttps://doi.org/10.3390/gels11020096
dc.identifier.volume11en_US
dc.identifier.wosWOS:001431888900001
dc.identifier.wosqualityQ1
dc.language.isoenen_US
dc.publisherMdpien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHybrid Hydrogelsen_US
dc.subjectProtein-Polymer Conjugatesen_US
dc.subjectPegylationen_US
dc.titleHydrogels From Protein-Polymer Conjugates: a Pathway To Next-Generation Biomaterialsen_US
dc.typeArticleen_US
dspace.entity.typePublication

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