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In silico identification of novel and selective monoamine oxidase B inhibitors
(SPRINGER WIEN, 2013)
Monoamine oxidases (MAO) A and B are flavin adenine dinucleotides containing enzymes bound to the mitochondrial outer membranes of the cells of the brain liver intestine and placenta as well as platelets. Recently selective ...
Exploration of the binding pocket of histone deacetylases: the design of potent and isoform-selective inhibitors
(Tübitak, 2017)
Histone deacetylases (HDACs) are enzymes that act on histone proteins to remove the acetyl group and thereby regulate the
chromatin state. HDACs act not only on histone protein but also nonhistone proteins that are key ...
Considerations and Confusions about theRegulatory Focus Theory and a Future Agendafor Researchers in Marketing
(Boğaziçi Üniversitesi, İktisadi ve İdari Bilimler Fakültesi, 2017)
The regulatory focus theory is the mark of a paradigm shift away from a unidimensional
hedonism towards a multiplicity of regulatory foci. It possesses great explanatory power;
however a lot remains unresolved despite a ...
Levant’ta büyük oyun: Doğu Akdeniz’in enerji jeopolitiği
(Uluslararası İlişkiler Konseyi Derneği İktisadi İşletmesi, 2012)
Levant Bölgesi’ndeki ticaret sisteminden başlayarak bölgenin hidrokarbon jeopolitiğine geçiş sürecine kadar uzanan tarihsel gelişimin uzun erimli (longue dureé) bakış açısıyla incelendiği bu çalışmada, bölgenin günümüzdeki ...
Debating Eurasia: Political Travels of a Geographical Concept in Turkey
(Uluslararası İlişkiler Konseyi Derneği, 2019)
This article reviews the ways in which various actors in Turkey have used the terms 'Eurasia' and 'Eurasianism' since the end of the Cold War. It presents two arguments. First, compared to Russian Eurasianism, it is difficult ...
Land Use And Land Cover Classification Of Sentinel 2-A: St Petersburg Case Study
(International Society for Photogrammetry and Remote Sensing, 2019)
Land use and land cover (LULC) maps in many areas have been used by companies, government offices, municipalities, and ministries. Accurate classification for LULC using remotely sensed data requires State of Art classification ...
Drug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening Methodologies
(Frontiers Media Sa, 2016)
The diverse cerebral mechanisms implicated in Central Nervous System (CNS) diseases together with the heterogeneous and overlapping nature of phenotypes indicated that multitarget strategies may be appropriate for the ...
Revenue management with minimax regret negotiations
(Pergamon-Elsevıer Scıence Ltd, 2016)
We study the dynamic bilateral price negotiations from the perspective of a monopolist seller. We first study the classical static problem with an added uncertainty feature. Next, we review the dynamic negotiation problem, ...
Modeling of Wind Effects on Stratified Flows in Open Channels: A Model for the Istanbul Strait (Bosphorus)
(2016)
Stratified flows in open channels arise as a result of density or surface level differences. If the channel is connected to a basin at one or both ends, strong winds originating from the basin cause the "wind setup" effect ...
A Bayesian approach to developing a strategic early warning system for the French milk market
(Halmstad University, 2017)
A new approach is provided in our paper for creating a strategic early warning system allowing the estimation of the future state of the milk market as scenarios. This is in line with the recent call from the EU commission ...