Browsing Mühendislik ve Doğa Bilimleri Fakültesi by Title
Now showing items 337-356 of 750
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Identification of Alternative Allosteric Sites in Glycolytic Enzymes for Potential Use as Species-Specific Drug Targets
(Frontiers Media, 2020)Three allosteric glycolytic enzymes, phosphofructokinase, glyceraldehyde-3 phosphate dehydrogenase and pyruvate kinase, associated with bacterial, parasitic and human species, were explored to identify potential allosteric ... -
Identification of potential inhibitors of human methionine aminopeptidase (type II) for cancer therapy: Structure-based virtual screening, ADMET prediction and molecular dynamics studies
(Elsevier, 2020)Methionine Aminopeptidases MetAPs are divalent-cofactor dependent enzymes that are responsible for the cleavage of the initiator Methionine from the nascent polypeptides. MetAPs are classified into two isoforms: namely, ... -
Identification of potential isoform-selective histone deacetylase inhibitors for cancer therapy: a combined approach of structure-based virtual screening ADMET prediction and molecular dynamics simulation assay
(Taylor & Francis Inc, 2018)Histone deacetylases (HDACs) have gained increased attention as targets for anticancer drug design and development. HDAC inhibitors have proven to be effective for reversing the malignant phenotype in HDAC-dependent cancer ... -
IEEE 802.15.4a Based Ultra Wideband Systems for Coexistence with Primary Users
(IEEE, 2015)Peaceful coexistence is a major implementation issue for both cognitive radios and ultra wideband (UWB) systems. Accordingly the UWB impulse radio (UWB-IR) based Wireless Personal Area Network (WPAN) standard IEEE 802.15.4a ... -
IEEE 802.15.7r1 Reference Channel Models for Visible Light Communications
(IEEE-Inst Electrical Electronics Engineers Inc, 2017)The IEEE has established the standardization group 802.15.7r1 "Short Range Optical Wireless Communications", which is currently in the process of developing a standard for visible light communication (VLC). As with any ... -
Implementation of a SDN (Software defined network)
(International Institute of Informatics and Systemics IIIS, 2014)Improving resource efficiency enhancing network security and achieving simpler network management have become the main goals for networking in the previous years. To accomplish these ideas an efficient routing traffic ... -
Importance of Regional Differences in Brain Throughout Aging for Down Syndrome
(Association for Computing Machinery, 2018)Down syndrome (DS) which affects approximately one in 700 live births is caused by an extra copy of the long arm of human chromosome 21 (HSA21). Statistical analysis has been done for understanding the protein expression ... -
An Improved Adaptive Subspace Tracking Algorithm Based on Approximated Power Iteration
(IEEE-INST Electrical Electronics Engineers Inc, 2018)A subspace tracking technique has drawn a lot of attentions due to its wide applications. The main objective of this approach is to estimate signal or noise subspace basis for the sample covariance matrix. In this paper ... -
Improvement of indoor positioning accuracy of ultra-wide band sensors by using big bang-big crunch optimization method
(Pamukkale Univ, 2018)Ultra-wide Band technology is an emerging technology that offers successful solutions in many indoor positioning systems and performs better than other methods. In this study an indoor positioning system using Ultra-wide ... -
Improving Energy-Efficiency of WSNs through LEFCA
(Sage Publications Inc, 2016)Wireless sensor networks (WSNs) have become an important part of our lives as they can be used in vast application areas from disaster relief to health care. As a consequence the life span and the energy consumption of a ... -
Improving OpenCL programmability with the Heterogeneous Programming Library
(Elsevier Science Bv, 2015)The use of heterogeneous devices is becoming increasingly widespread. Their main drawback is their low programmability due to the large amount of details that must be handled. Another important problem is the reduced code ... -
Improving performances of suboptimal greedy iterative biclustering heuristics via localization
(Oxford University Press, 2010)Motivation: Biclustering gene expression data is the problem of extracting submatrices of genes and conditions exhibiting significant correlation across both the rows and the columns of a data matrix of expression values. ... -
In silico design of novel and highly selective lysine-specific histone demethylase inhibitors
(Scientific Technical Research Council Turkey-Tubitak, 2011)Histone lysine-specific demethylase (LSD1) is involved in a wide range of epigenetic processes and plays important roles in gene silencing DNA transcription DNA replication DNA repair and heterochromatin formation. Its ... -
In silico identification of critical proteins associated with learning process and immune system for Down syndrome
(Public Library Science, 2019)Understanding expression levels of proteins and their interactions is a key factor to diagnose and explain the Down syndrome which can be considered as the most prevalent reason of intellectual disability in human beings. ... -
In silico identification of novel and selective monoamine oxidase B inhibitors
(SPRINGER WIEN, 2013)Monoamine oxidases (MAO) A and B are flavin adenine dinucleotides containing enzymes bound to the mitochondrial outer membranes of the cells of the brain liver intestine and placenta as well as platelets. Recently selective ... -
In Silico Modeling of Dopamine Transporter and Design of Novel Neuroprotective Agents
(Amer Chemical Soc, 2016)[Abstract Not Available] -
In situ steady state fluorescence (SSF) technique to study drying of PAAm hydrogels made of various cross-linker contents
(Elsevier Science, 2009)Drying experiments of polyacrylamide (PAAm) gels were performed using steady-state fluorescence (SSF) spectrometer. Pyranine (P) was introduced as a fluorescence probe and intensity of P from various crosslinker content ... -
Influence of pH on the optical and structural properties of spin coated CeO2-TiO2 thin films prepared by sol-gel process
(Elsevier Science Bv, 2007)Optical and structural properties of mixed CeO2-TiO2 thin films have been investigated by varying the pH of the coating sol. The films were prepared by sol-gel process using spin-coating technique with a spin speed of 2500 ... -
Information Theoretical Performance Analysis and Optimisation of Cooperative Underwater Acoustic Communication Systems
(Inst Engineering Technology-IET, 2016)In this study the authors investigate the information theoretical limits on the performance of single-carrier cooperative underwater acoustic communication systems in the presence of intersymbol interference. The authors ... -
Information theoretical performance limits of single-carrier underwater acoustic systems
(Inst Engineering Technology-IET, 2014)In this study the authors investigate the information theoretical limits on the performance of point-to-point single-carrier acoustic systems over frequency-selective underwater channels with intersymbol interference. Under ...