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In silico screening of multi target drug for alzheimer'sdisease and parkinson's disease using pharmacophore-baseddrug discovery approach
(Kadir Has Üniversitesi, 2019)
Research on neurodegenerative diseases (NDD), commonly known as Alzheimer's and Parkinson's disease are the most important concern in this aging society. Among the other causes the main suspected reasons are the production ...
Rolün inşa sürecinde hayal gücü ve duyusal hafiza : rol için yapilan sicak sandalye çalişmasinin stanislavski yöntemi eşliğinde incelenmesi
(Kadir Has Üniversitesi, 2019)
Rol kisisine yonelik yapilan sicak sandalye calismasina odaklanan bu tez calismanin bir role hazirlik surecinde oyuncuya ne tur katkilar saglayabilecegi meselesini ana sorusu olarak belirlemistir. Bu soru uzerinden calisma ...
Synthesis molecular modeling in vivo study and anticancer activity of 124-triazole containing hydrazide-hydrazones derived from (S)-naproxen
(Wiley-VCH Verlag GmbH, 2019)
A new series of 124-triazole containing hydrazide-hydrazones derived from (S)-naproxen (7a-m) was synthesized in this study. The structures of these compounds were characterized by spectral (Fourier-transform infrared ...
Rapidly Varying Sparse Channel Tracking with Hybrid Kalman-OMP Algorithm
(Springer, 2019)
It is expected from future communication standards that channel estimation algorithms should be able to operate over very fast varying frequency selective channel models. Therefore in this study autoregressive (AR) modeled ...
Examining the stability of binding modes of the co-crystallized inhibitors of human HDAC8 by molecular dynamics simulation
(Taylor & Francis Inc, 2019)
Histone deacetylase (HDAC) 8 has been implicated as a potential therapeutic target in a variety of cancers neurodegenerative disorders metabolic dysregulation and autoimmune and inflammatory diseases. Several nonselective ...
Ligand-binding affinity of alternative conformers of human beta(2)-adrenergic receptor in the presence of intracellular loop 3 (ICL3) and their potential use in virtual screening studies
(Wiley, 2019)
This study investigates the structural distinctiveness of orthosteric ligand-binding sites of several human beta(2) adrenergic receptor (beta(2)-AR) conformations that have been obtained from a set of independent molecular ...
How is the Big Five related to moral and political convictions: The moderating role of the WEIRDness of the culture
(Pergamon-Elsevier Science Ltd, 2019)
There has been extensive research on how the Big Five personality traits are related to political orientation and endorsement of moral foundations. However, recent findings suggest that these relationships may not be ...
A fuzzy ANP-based GRA approach to evaluate ERP packages
(IGI Global, 2019)
One of the major problems that most companies face with during the implementation of an ERP system is to determine the best satisfying ERP software based on their needs and expectations. Because an improperly selected ERP ...
Transitional Butterworth-Chebyshev Filters
(IEEE, 2019)
Filters which are studied in this paper have properties that lie between those of the Butterworth and Chebyshev filters. So it is appropriate to call this kind of filters as transitional Butterworth-Chebyshev filters. In ...
An investigation of financial literacy money ethics and time preferences among college students: A structural equation model
(Emerald Group Publishing Limited, 2019)
Purpose: Financial literacy has a strong influence on financial well-being and it is a concept especially important for college students who start to develop their financial habits. The purpose of this paper is to examine ...