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Lipoprotein lipase gene polymorphism and lipid profile in coronary artery disease
(COLL AMER PATHOLOGISTS, 2004)
Context.-Lipoprotein lipase (LPL) plays a central role in lipid metabolism hydrolyzing triglyceride in chylomicrons and very-low-density lipoproteins. The PvuII polymorphic variant of LPL gene is common and might affect ...
Apolipoprotein E polymorphism in Turkish subjects with Type 2 diabetes mellitus: Allele frequency and relation to serum lipid concentrations
(EDITRICE KURTIS S R L, 2004)
The role of apolipoprotein E (apoE) genotypes in modulating plasma lipid and apolipoprotein levels was studied in 112 patients with Type 2 diabetes mellitus (T2DM) and 94 healthy individuals. ApoE genotypes were identified ...
Protective effects of a calcium channel blocker on apoptosis in thymus of neonatal STZ-diabetic rats
(Elsevier GMBH Urban & Fischer Verlag, 2005)
Streptozotocin (STZ) is known to induce insulin-dependent diabetes in experimental animals. In STZ-induced diabetes atrophy of the thymus is caused by elevated intracellular calcium levels leading to apoptosis. Hyperglycemia ...
Polymorphisms at the ligand binding site of the vitamin D receptor gene and osteomalacia
(Hindawi Ltd, 2005)
Vitamin D receptor (VDR) gene polymorphisms have been suggested as possible determinants of bone mineral density (BMD) and calcium metabolism. In this study our aim was to determine whether there is an association between ...
DNA polymorphism of Pvu II site in the lipoprotein lipase gene in patients with non-insulin dependent diabetes mellitus
(Wiley, 2005)
We studied the effect of variation at the lipoprotein lipase (LPL) gene locus on the susceptibility of individuals with non-insulin dependent diabetes mellitus (NIDDM) in a population of 110 NIDDM patients and 91 controls. ...
Genetic variations of the apolipoprotein B gene in Turkish patients with coronary artery disease
(Taylor & Francis Ltd, 2005)
Background: The results of studies that clarify the association of genetic markers at the apolipoprotein B (apo B) gene (EcoRI and XbaI polymorphisms) with coronary artery disease (CAD) are not consistent and suggest that ...
Thiols malonaldehyde status in the Turkish and total antioxidant patients with type 2 diabetes mellitus
(Tohoku Univ Medical Press, 2003)
Non-insulin-dependent (Type 2) diabetes mellitus (NIDDM) is a risk factor for cardiovascular diseases (CVD). Oxidative stress mechanisms are often reported to be implied in type 2 diabetes mellitus. In order to determine ...
Vitamin D receptor alleles bone mineral density and turnover in postmenopausal osteoporotic and healthy women
(Karger, 2004)
Objective: Vitamin D receptor (VDR) gene polymorphisms and bone metabolic markers were investigated as potential genetic markers for osteoporosis in postmenopausal Turkish women. The relationship between their VDR gene ...
Effect of abdominal obesity on insulin resistance and the components of the metabolic syndrome: Evidence supporting obesity as the central feature
(F D-Communications Inc., 2003)
Background: Metabolic syndrome includes abdominal obesity diabetes type 2 hypertension dyslipidemia derangements of fibrinolysis and atherosclerosis. Since abdominal obesity is one of the major components of the insulin ...
The interrelationship between insulin secretion and action in Type 2 diabetes mellitus with different degrees of obesity: Evidence supporting central obesity
(Editrice Kurtis S R L, 2003)
This paper investigates the relative role of the impairment of insulin secretion and action in the pathogenesis of Type 2 diabetes mellitus (T2DM). The parameters indicating insulin secretion and action were calculated ...